Results 11 to 20 of about 7,485,897 (373)

Enhancement of acarbose production by genetic engineering and fed-batch fermentation strategy in Actinoplanes sp. SIPI12-34

Microbial Cell Factories, 2022
Background Acarbose, as an alpha-glucosidase inhibitor, is widely used clinically to treat type II diabetes. In its industrial production, Actinoplanes sp. SE50/110 is used as the production strain.
Zhenxin Li, Songbai Yang, Zhengyu Zhang, Yuanjie Wu, Jiawei Tang, Luoju Wang, Shaoxin Chen   +6 more
doaj   +1 more source

The Pharmaceutical Industry in 2022: An Analysis of FDA Drug Approvals from the Perspective of Molecules

Molecules, 2023
While 2021 ended with the world engulfed in the COVID-19 Omicron wave, 2022 has ended in almost all countries, except China, with COVID-19 being likened to the flu. In this context, the U.S.
B. G. de la Torre, F. Albericio
semanticscholar   +1 more source

Phenolic Constituents from the Stems of Morus nigra and their α-Glucosidase Inhibitory Activities

Pharmaceutical Fronts, 2021
A new sanggenon-type flavanone, nigragenon F (1), together with 11 known compounds, trans-resveratrol (2), (E)-4-isopentenyl-3,5,2′,4′-tetrahydroxystilbene (3), notabilisin E (4), notabilisin A (5), morusin (6), petalopurpurenol (7), 8-geranyl-5,7 ...
Ling-Ling Wang, Liang-Jin Xu, Meng-Jie Ma, Chun-Yue Huang, Tong Wu, Xiao Hu   +5 more
doaj   +1 more source

Enhanced Efficacy and Reduced Hepatotoxicity by Combination of Gnaphalium affine Extract and Benzbromarone in the Treatment of Rats with Hyperuricemic Nephropathy

Pharmaceutical Fronts, 2021
Simultaneous oral intake of herbal medicine with chemical drugs may result in beneficial pharmacodynamic efficacy, including additive and synergistic effects with reduced toxicity. Gnaphalium affine D. Don (GAD) is a traditional Chinese Medicine that has
Fei Liu, Xi-Zi Liu, Qian Yang, Shi-Yi Han, Si-Yang Fan   +4 more
doaj   +1 more source

Behind the French controversy over the medical treatment of Covid-19: The role of the drug industry

Journal of Sociology, 2020
This article explores the stakes of the very intense controversy that has developed in France around the medical treatment of Covid-19 (which finds some parallels in the United States of America).
L. Mucchielli
semanticscholar   +1 more source

GPs’ perceptions of their relationship with the pharmaceutical industry: a qualitative study

BJGP Open, 2021
Background: The pharmaceutical industry invests heavily in promoting medications to physicians. This promotion may influence physicians’ prescribing behaviour and lead to inappropriately increased prescribing rates.
James Larkin, Ivana Pericin, Maurice Collins, Susan M Smith, David Byrne, Frank Moriarty   +5 more
doaj   +1 more source

Natural products in drug discovery: advances and opportunities

Nature reviews. Drug discovery, 2021
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
A. Atanasov, S. Zotchev, V. Dirsch, Ilkay Erdogan Maciej Judith M. Davide Wolfram Rudolf Edw Orhan Banach Rollinger Barreca Weckwerth Bauer Bay, I. Orhan, M. Banach, J. Rollinger, D. Barreca, W. Weckwerth, R. Bauer, E. Bayer, M. Majeed, A. Bishayee, V. Bochkov, G. Bonn, N. Braidy, F. Bucar, A. Cifuentes, G. D’Onofrio, Michael A. Bodkin, M. Diederich, A. Dinkova-Kostova, T. Efferth, K. El Bairi, N. Arkells, Tai-Ping Fan, B. Fiebich, M. Freissmuth, M. Georgiev, S. Gibbons, K. Godfrey, Christian W. Gruber, J. Heer, Lukas A. Huber, E. Ibáñez, A. Kijjoa, A. Kiss, Aiping Lu, F. A. Macias, Mark J. S. Miller, A. Mocan, Rolf Müller, Ferdinando Nicoletti, George Perry, V. Pittalà, L. Rastrelli, M. Ristow, G. Russo, A. S. Silva, D. Schuster, H. Sheridan, K. Skalicka‐Woźniak, L. Skaltsounis, E. Sobarzo-Sánchez, D. Bredt, H. Stuppner, A. Sureda, N. Tzvetkov, R. A. Vacca, Bharat B. Aggarwal, M. Battino, F. Giampieri, M. Wink, J. Wolfender, Jianbo Xiao, A. Yeung, G. Lizard, M. Popp, Michael Heinrich, I. Berindan‐Neagoe, M. Stadler, M. Daglia, R. Verpoorte, C. Supuran   +73 more
semanticscholar   +1 more source

Pharmaceutical procurement among public sector procurers in CARICOM

Revista Panamericana de Salud Pública, 2021
Objective. To examine multiple aspects of the medicines in CARICOM procurement markets, including manufacturer headquarters location, regulatory history, and type (innovator versus generic); the proportion of World Health Organization (WHO) essential ...
Charles Preston, Claire King, Maryam Hinds, Francis Burnett, Rian Marie Extavour   +4 more
doaj   +1 more source

Procedure for Reviewing Pharmaceutical Inspections in the Eurasian Economic Union (Review)

Разработка и регистрация лекарственных средств, 2021
Introduction. The article discusses significant changes in the procedure for pharmaceutical inspection of drug manufacturers for compliance with the requirements of the rules of good manufacturing practice (GMP) of the Eurasian Economic Union (EAEU ...
A. P. Meshkovskiy, V. V. Beregovykh, V. N. Shestakov, N. V. Pyatigorskaya, Zh. I. Aladysheva, N. S. Nikolenko, A. M. Pyatigorskiy, E. I. Nesterkina   +7 more
doaj   +1 more source

Anticoccidial drugs of the livestock industry [PDF]

Parasitology Research, 2019
Coccidiosis is a parasitic disease of a wide variety of animals caused by coccidian protozoa. The coccidia are responsible for major economic losses of the livestock industry. For example, the annual cost due to coccidiosis to the global poultry industry has been estimated to exceed US$ 3 billion annually.
Sandra Noack, H. David Chapman, Paul M. Selzer   +2 more
openaire   +3 more sources