Results 11 to 20 of about 941,777 (314)

Teaching medical students how to interact with the pharmaceutical industry: A scoping review

open access: yesGMS Journal for Medical Education, 2022
Objectives: The influence of the pharmaceutical industry is of significant concern in physician prescribing decisions; medical students may not be fully equipped with the knowledge or skills to manage interactions with industry prior to graduation.
Farah, Samiyah, Bilszta, Justin L.
doaj   +1 more source

The rule of five should not impede anti-parasitic drug development. [PDF]

open access: yes, 2017
The "rule of 5" has become a mainstay of decision-making in the pharmaceutical industry as well as in nonindustrial (academic and institutional) drug development.
Lipinski, Christopher A   +1 more
core   +1 more source

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

open access: yes, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad   +4 more
core   +1 more source

Physician-industry relationship and conflicts of interest: Historical, normative aspects, negative impact and proposals

open access: yesIatreia, 2019
This article presents a narrative review of the relationship between physicians and industry (RPI), which includes pharmaceutical, devices and supplements’ industries and the conflicts of interest that arise from this relationship.
Genta Mesa, Giuseppe   +1 more
doaj   +1 more source

Preparation and Study on the Single-Crystal Structure of Flurbiprofen–Salicylamide Co-crystal

open access: yesPharmaceutical Fronts, 2023
Co-crystals can improve the physicochemical properties of pharmaceutical active ingredients, and thus have great potential in improving drug performance.
Jia-Wei Hou   +6 more
doaj   +1 more source

The Effects of Industry Sponsorship on Comparator Selection in Trial Registrations for Neuropsychiatric Conditions in Children [PDF]

open access: yes, 2013
Pediatric populations continue to be understudied in clinical drug trials despite the increasing use of pharmacotherapy in children, particularly with psychotropic drugs.
Bourgeois, Florence T.   +3 more
core   +3 more sources

Structural Characterization of Chemical Compounds Based on Their Fragmentation Rules in Sophorae Fructus by UPLC-QTOF-MS/MS

open access: yesPharmaceutical Fronts, 2022
This study aims to identify the chemical components in Sophorae Fructus, and explore the mass spectrometric cleavage rules using the UPLC-Q-TOF-MS/MS method. The main characteristic fragments of the compounds were analyzed by electrospray ionization (ESI)
Zi-Hui He   +3 more
doaj   +1 more source

Recent Research Advances in Small-Molecule Pan-PIM Inhibitors

open access: yesPharmaceutical Fronts, 2022
PIM kinase is consequently emerging as a promising target for cancer therapeutics and immunomodulation. PIM kinases are overexpressed in a variety of hematological malignancies and solid tumors, and their inhibition has become a strong therapeutic ...
Lei Xu   +5 more
doaj   +1 more source

Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2022
COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa   +4 more
doaj   +1 more source

Enantioselective aza-Michael Cyclization Reaction Catalyzed by Quinine-Derived Monoquaternary Ammonium Salts: an Effective Route to Synthesize Letermovir

open access: yesPharmaceutical Fronts, 2021
A series of mono- or bis-quaternary ammonium salts derived from cinchonidine or quinine was synthesized and screened as potent phase-transfer catalysts for the reaction of aza-Michael cyclization, the key step in the synthesis of letermovir.
Liang Chen   +7 more
doaj   +1 more source

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