Results 21 to 30 of about 7,485,897 (373)

Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems

open access: yesPolymers, 2023
In the last four decades, nanotechnology has gained momentum with no sign of slowing down. The application of inventions or products from nanotechnology has revolutionised all aspects of everyday life ranging from medical applications to its impact on ...
Azeez Yusuf   +4 more
semanticscholar   +1 more source

Preparation and Study on the Single-Crystal Structure of Flurbiprofen–Salicylamide Co-crystal

open access: yesPharmaceutical Fronts, 2023
Co-crystals can improve the physicochemical properties of pharmaceutical active ingredients, and thus have great potential in improving drug performance.
Jia-Wei Hou   +6 more
doaj   +1 more source

Applications of single-cell RNA sequencing in drug discovery and development

open access: yesNature reviews. Drug discovery, 2023
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods, together with associated computational tools and the growing availability of public data resources, are transforming drug discovery and development.
Bram Van de Sande   +16 more
semanticscholar   +1 more source

The Pharmaceutical Industry in 2020. An Analysis of FDA Drug Approvals from the Perspective of Molecules

open access: yesMolecules, 2021
Although the pharmaceutical industry will remember 2020 as the year of COVID-19, it is important to highlight that this year has been the second-best—together with 1996—in terms of the number of drugs accepted by the US Food and Drug Administration (FDA).
B. G. Torre, F. Albericio
semanticscholar   +1 more source

Improvement of Nemadectin Production by Overexpressing the Regulatory Gene nemR and Nemadectin Biosynthetic Gene Cluster in Streptomyces Cyaneogriseus

open access: yesPharmaceutical Fronts, 2020
Nemadectin, a 16-member macrocyclic lactone antiparasitic antibiotic, is produced by Streptomyces cyaneogriseus subspecies noncyanogenus. Moxidectin, a C-23 oximate derivative of nemadectin, is widely used as a pesticide due to its broad-spectrum, highly
Yuan-Jie Wu   +3 more
doaj   +1 more source

Teaching medical students how to interact with the pharmaceutical industry: A scoping review

open access: yesGMS Journal for Medical Education, 2022
Objectives: The influence of the pharmaceutical industry is of significant concern in physician prescribing decisions; medical students may not be fully equipped with the knowledge or skills to manage interactions with industry prior to graduation.
Farah, Samiyah, Bilszta, Justin L.
doaj   +1 more source

The rule of five should not impede anti-parasitic drug development. [PDF]

open access: yes, 2017
The "rule of 5" has become a mainstay of decision-making in the pharmaceutical industry as well as in nonindustrial (academic and institutional) drug development.
Lipinski, Christopher A   +1 more
core   +1 more source

Physician-industry relationship and conflicts of interest: Historical, normative aspects, negative impact and proposals

open access: yesIatreia, 2019
This article presents a narrative review of the relationship between physicians and industry (RPI), which includes pharmaceutical, devices and supplements’ industries and the conflicts of interest that arise from this relationship.
Genta Mesa, Giuseppe   +1 more
doaj   +1 more source

Risk and Reward in the Orphan Drug Industry

open access: yesJournal of Portfolio Management, 2018
Thanks to a combination of scientific advances and economic incentives, the development of therapeutics to treat rare or orphan diseases has grown dramatically in recent years.
A. Lo, Richard T. Thakor
semanticscholar   +1 more source

Ceftiofur-loaded PHBV microparticles: A potential formulation for a long-acting antibiotic to treat animal infections [PDF]

open access: yes, 2012
Indexación: Web of Science; ScieloBackground: The infectious diseases in the livestock breeding industry represent a significant drawback that generates substantial economic loss and have led to the indiscriminate use of antibiotics.
Constandil   +5 more
core   +1 more source

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