Results 31 to 40 of about 7,614,121 (392)

Preparation and Study on the Single-Crystal Structure of Flurbiprofen–Salicylamide Co-crystal

open access: yesPharmaceutical Fronts, 2023
Co-crystals can improve the physicochemical properties of pharmaceutical active ingredients, and thus have great potential in improving drug performance.
Jia-Wei Hou   +6 more
doaj   +1 more source

Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems

open access: yesPolymers, 2023
In the last four decades, nanotechnology has gained momentum with no sign of slowing down. The application of inventions or products from nanotechnology has revolutionised all aspects of everyday life ranging from medical applications to its impact on ...
Azeez Yusuf   +4 more
semanticscholar   +1 more source

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

open access: yes, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad   +4 more
core   +1 more source

Applications of single-cell RNA sequencing in drug discovery and development

open access: yesNature reviews. Drug discovery, 2023
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods, together with associated computational tools and the growing availability of public data resources, are transforming drug discovery and development.
Bram Van de Sande   +16 more
semanticscholar   +1 more source

The rule of five should not impede anti-parasitic drug development. [PDF]

open access: yes, 2017
The "rule of 5" has become a mainstay of decision-making in the pharmaceutical industry as well as in nonindustrial (academic and institutional) drug development.
Lipinski, Christopher A   +1 more
core   +1 more source

The Pharmaceutical Industry in 2020. An Analysis of FDA Drug Approvals from the Perspective of Molecules

open access: yesMolecules, 2021
Although the pharmaceutical industry will remember 2020 as the year of COVID-19, it is important to highlight that this year has been the second-best—together with 1996—in terms of the number of drugs accepted by the US Food and Drug Administration (FDA).
B. G. Torre, F. Albericio
semanticscholar   +1 more source

Teaching medical students how to interact with the pharmaceutical industry: A scoping review

open access: yesGMS Journal for Medical Education, 2022
Objectives: The influence of the pharmaceutical industry is of significant concern in physician prescribing decisions; medical students may not be fully equipped with the knowledge or skills to manage interactions with industry prior to graduation.
Farah, Samiyah, Bilszta, Justin L.
doaj   +1 more source

Risk and Reward in the Orphan Drug Industry

open access: yesJournal of Portfolio Management, 2018
Thanks to a combination of scientific advances and economic incentives, the development of therapeutics to treat rare or orphan diseases has grown dramatically in recent years.
A. Lo, Richard T. Thakor
semanticscholar   +1 more source

A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]

open access: yes, 2012
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core   +2 more sources

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