Results 31 to 40 of about 7,485,897 (373)

A Blockchain and Machine Learning-Based Drug Supply Chain Management and Recommendation System for Smart Pharmaceutical Industry

open access: yesElectronics, 2020
From the last decade, pharmaceutical companies are facing difficulties in tracking their products during the supply chain process, allowing the counterfeiters to add their fake medicines into the market.
Khizar Abbas   +3 more
semanticscholar   +1 more source

The Dynamic Spillovers of Entry: An Application to the Generic Drug Industry

open access: yesManagement Sciences, 2018
This paper examines whether experience from entry in one market can potentially enhance profitability at a future market opportunity for a related product.
A. Gallant, H. Hong, Ahmed Khwaja
semanticscholar   +1 more source

Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2022
COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa   +4 more
doaj   +1 more source

Hydrophilic Matrices for Oral Control Drug Delivery [PDF]

open access: yes, 2015
Oral controlled drug delivery has gathered tremendous attention over the years due to its many advantages over conventional dosage forms. Polymer-based matrices have become an integral part of the pharmaceutical industry. Hydrophilic matrices are capable
Conway, Barbara R, Ghori, Muhammad U.
core   +1 more source

Structural Characterization of Chemical Compounds Based on Their Fragmentation Rules in Sophorae Fructus by UPLC-QTOF-MS/MS

open access: yesPharmaceutical Fronts, 2022
This study aims to identify the chemical components in Sophorae Fructus, and explore the mass spectrometric cleavage rules using the UPLC-Q-TOF-MS/MS method. The main characteristic fragments of the compounds were analyzed by electrospray ionization (ESI)
Zi-Hui He   +3 more
doaj   +1 more source

Using transcriptomics to guide lead optimization in drug discovery projects : lessons learned from the QSTAR project [PDF]

open access: yes, 2015
The pharmaceutical industry is faced with steadily declining R&D efficiency which results in fewer drugs reaching the market despite increased investment.
Bender, Andreas   +10 more
core   +2 more sources

Extending the in vivo Half-Life of Adalimumab Fab via Sortase A-Mediated Conjugation of Adalimumab Fab with Modified Fatty Acids

open access: yesPharmaceutical Fronts, 2020
Adalimumab, a full-length monoclonal antibody, is widely used as an anti-tumor necrosis factor-α (anti-TNF-α) agent. In this article, we aimed to prolong the in vivo half-life of adalimumab antigen-binding fragment (Fab) through Sortase A (SrtA)-mediated
Qing-Bin Zhang   +5 more
doaj   +1 more source

Recent Research Advances in Small-Molecule Pan-PIM Inhibitors

open access: yesPharmaceutical Fronts, 2022
PIM kinase is consequently emerging as a promising target for cancer therapeutics and immunomodulation. PIM kinases are overexpressed in a variety of hematological malignancies and solid tumors, and their inhibition has become a strong therapeutic ...
Lei Xu   +5 more
doaj   +1 more source

Making regulation responsive to commercial interests: streamlining drug industry watchdogs [PDF]

open access: yes, 2002
New prescription drugs are developed and tested for quality, safety, and efficacy by the pharmaceutical industry, and little or no drug testing is conducted by governments in modern industrialised countries.
Abraham, John
core   +2 more sources

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