Results 41 to 50 of about 7,485,897 (373)
Pharmaceutical Fronts, 2021 A series of mono- or bis-quaternary ammonium salts derived from cinchonidine or quinine was synthesized and screened as potent phase-transfer catalysts for the reaction of aza-Michael cyclization, the key step in the synthesis of letermovir.
Liang Chen +7 more
doaj +1 more source
Prevalence of tablet splitting in a Brazilian tertiary care hospital
Pharmacy Practice, 2020 Background: Although a highly common practice in hospital care, tablet splitting can cause dose variation and reduce drug stability, both of which impair drug therapy. Objective: To determine the overall prevalence of tablet splitting in hospital care
Vivianne V. Melo +6 more
doaj +1 more source
Drugs, Industry, and Academia [PDF]
Science, 2008 This week, international academic and industry leaders, investors, and policy-makers participated in the Biotechnology Industry Organization9s International Convention in San Diego, a reminder that prospects for new drugs seem bleak. Only 17 new molecular entities were approved by the U.S.
openaire +3 more sources
Human organs-on-chips for disease modelling, drug development and personalized medicine
Nature reviews genetics, 2022 The failure of animal models to predict therapeutic responses in humans is a major problem that also brings into question their use for basic research.
D. Ingber
semanticscholar +1 more source
Chiral Analysis of the Key Intermediates of Tenofovir Alafenamide Fumarate
Pharmaceutical Fronts, 2023 (R)-Tenofovir phenyl ester ((R)-1) and (R)-tenofovir diphenyl ester ((R)-2) are key intermediates for the practical synthesis of tenofovir alafenamide fumarate, which is a mainstay antiretroviral for the treatment of chronic hepatitis B and HIV-1 ...
Man Li, Ting Zhou, Qing-Wen Zhang
doaj +1 more source
Application of Digital Image Processing in Drug Industry
, 2017 Digital Image Processing is a very vast field It has many applications in every field and one such application is in drug industry. Drug Industry is leading industry.
Huvaida Manzoor
semanticscholar +1 more source
The Price of Progress: Funding and Financing Alzheimer\u27s Disease Drug Development [PDF]
, 2018 Introduction Advancing research and treatment for Alzheimer\u27s disease (AD) and the search for effective treatments depend on a complex financial ecosystem involving federal, state, industry, advocacy, venture capital, and philanthropy funding ...
Cummings, Jeffrey +2 more
core +2 more sources
Regulating the drugs industry transparently [PDF]
BMJ, 2005 Over the past 10-15 years, drug regulatory authorities in the United Kingdom and elsewhere have streamlined and accelerated the review of new drugs in response to claims by the pharmaceutical industry that over-regulation was stifling innovation.1,2 Despite these policies, the number of new molecular entities—a standard measure of innovation in the ...
openaire +4 more sources
Accelerating antiviral drug discovery: lessons from COVID-19
Nature reviews. Drug discovery, 2023 During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and collaborative drug discovery efforts took place in academia and industry, culminating in several therapeutics being discovered, approved and deployed in a 2-year time frame ...
Annette von Delft +7 more
semanticscholar +1 more source
Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]
, 2020 For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad +4 more
core +1 more source