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Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]
Pharmaceutics, 2021 Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
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CPT: Pharmacometrics & Systems Pharmacology, 2021 Although the use of excipients is widespread, a thorough understanding of the drug interaction potential of these compounds remains a frequent topic of current research.
Savannah J. McFeely +4 more
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Effect of Lactic Acid Bacteria on the Pharmacokinetics and Metabolism of Ginsenosides in Mice
Pharmaceutics, 2021 This study aims to investigate the effect of lactic acid bacteria (LAB) on in vitro and in vivo metabolism and the pharmacokinetics of ginsenosides in mice.
Ji-Hyeon Jeon +5 more
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Pharmaceutics, 2021 Candesartan cilexetil (CC), a prodrug and highly effective antihypertensive agent, is a poorly soluble (BCS Class II) drug with limited bioavailability.
Surendra Poudel, Dong Wuk Kim
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Toxics, 2022 Fimasartan, amlodipine, and hydrochlorothiazide are commonly used in combination therapies as antihypertensive drugs. This study aimed to develop and validate an analytical method for fimasartan, its active and major metabolite fimasartan-amide ...
So-Yeon Jeon +6 more
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Pharmaceutics, 2021 We evaluated the bioavailability, liver distribution, and efficacy of silymarin-D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) solid dispersion (silymarin-SD) in rats with acetaminophen-induced hepatotoxicity (APAP) compared with silymarin ...
Im-Sook Song +4 more
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Clinical and Translational Science, 2022 Pharmacokinetic drug interactions precipitated by botanical and other natural products (NPs) remain critically understudied. Investigating these complex interactions is fraught with difficulties due to the methodologic and technical challenges associated
Emily J. Cox +5 more
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Pharmaceutics, 2023 Semisolid extrusion (SSE) three-dimensional (3D) printing uses drug-loaded paste for the printing process, which is capable of constructing intricate 3D structures.
Hyun Seok Yang, Dong Wuk Kim
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Pharmaceuticals, 2021 Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility.
Bhupendra Raj Giri +5 more
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Pharmaceutics, 2022 The poor aqueous solubility and/or permeability and thereby limited bioavailability largely restricts the pharmaco-therapeutic implications of potent anticancer drugs such as methotrexate (MTX).
Bhupendra Raj Giri +5 more
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