Results 11 to 20 of about 8,631,498 (387)
From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics
Clinical pharmacology and therapy, 2021 Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have evolved as important tools to inform rational dosing of antibiotics in individual patients with infections.
S. Wicha +6 more
semanticscholar +1 more source
Therapeutic Drug Monitoring, 2021 When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy, fixed doses were recommended by the manufacturer. Awareness of the potential for a more personalized dosing has led to development of methods to estimate MPA area under ...
S. Bergan +37 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2021 Importance Proactive therapeutic drug monitoring (TDM), defined as individualized drug dosing based on scheduled monitoring of serum drug levels, has been proposed as an alternative to standard therapy to maximize efficacy and safety of infliximab and ...
S. W. Syversen +32 more
semanticscholar +1 more source
Therapeutic drug monitoring in drug overdose [PDF]
British Journal of Clinical Pharmacology, 1999 The treatment of poisoned patients is still largely defined by history, clinical assessment and interpretation of ancillary investigations. Measurement of drug concentrations is clinically important for relatively few compounds. Most measurements form an adjunct to and should not be considered a substitute for clinical assessment.
Ian M Whyte, Andrew H. Dawson
openaire +7 more sources
Molecules, 2022 The third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), osimertinib, aumolertinib, and furmonertinib represent a new treatment option for patients with EGFR p.Thr790 Met (T790 M)-mutated non-small cell lung cancer ...
Ying Li +6 more
doaj +1 more source
Fayixue Zazhi, 2022 ObjectiveTo analyze the chemical structure of the interfering substance that affects the result of methamphetamine analysis in wastewater.MethodsA combination of GC-MS and liquid chromatography-quadrupole time-of-flight mass spectrometry （LC-QTOF-MS） was
ZHANG Ting-ting +4 more
doaj +1 more source
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Intensive Care Medicine, 2020 This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill adult patients in the intensive care unit (ICU).
M. Abdul-Aziz +15 more
semanticscholar +1 more source
Determination of five prostaglandin analogs in eyelash enhancing cosmetics by LC-MS/MS
Shanghai yufang yixue, 2022 ObjectiveTo determine bimatoprost， tafluprost ethyl amide， latanoprost， travoprost and tafluprost in eyelash enhancing cosmetics by establishing a LC-MS/MS method.MethodsThe samples were extracted with a 50% acetonitrile water solution. A salt mixture （
XU Yong +4 more
doaj +1 more source
Mass Fragmentation Characteristics of 4 Synthetic Cathinone Isomers [PDF]
Zhipu Xuebao, 2023 Synthetic cathinones, the designer analogs of the naturally occurring cathinone found in Khat, largely entered the recreational drug market at the end of the 2000s. They are a large class of new psychoactive substances (NPS) often used as substitutes for
JIA Wei;HU Shuang;LI Tao;LIU Cui-mei;WANG You-mei;HUA Zhen-dong
doaj +1 more source
Monitoring drug adherence [PDF]
Transplantation Reviews, 2015 Medication nonadherence is prevalent in transplant recipients and is a major reason for graft loss. The present review discusses the measurement of adherence in transplant recipients and strategies to improve adherence. SOURCES REVIEWED: Since adherence research is not confined to transplant recipients, our literature review included studies relevant ...
Sarah R. Lieber +5 more
openaire +3 more sources