Results 11 to 20 of about 9,044,537 (408)

online quantitative analysis, online process mass spectrometer, quadrupole mass spectrometer [PDF]

open access: yesZhipu Xuebao, 2023
As of October 2022, the United Nations Office on Drugs and Crime (UNODC) Early Warning Advisory (EWA) has monitored over 1 150 new psychoactive substances (NPS) that had appeared in 137 countries and territories, including 76 substances that were ...
LIU Cui-mei1   +5 more
doaj   +1 more source

Impact of COVID-19 on drug markets, use, harms and drug services in Europe

open access: yesJournal of Geography, Politics and Society, 2022
Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets
Alessandro Pirona   +12 more
doaj   +1 more source

A Simple UPLC/MS-MS Method for Simultaneous Determination of Lenvatinib and Telmisartan in Rat Plasma, and Its Application to Pharmacokinetic Drug-Drug Interaction Study

open access: yesMolecules, 2022
Lenvatinib is a multi-targeted tyrosine kinase inhibitor that inhibits tumor angiogenesis, but hypertension is the most common adverse reaction. Telmisartan is an angiotensin receptor blocker used to treat hypertension.
Yanjun Cui   +6 more
doaj   +1 more source

From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics

open access: yesClinical pharmacology and therapy, 2021
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have evolved as important tools to inform rational dosing of antibiotics in individual patients with infections.
S. Wicha   +6 more
semanticscholar   +1 more source

Development of UPLC-MS/MS Method to Study the Pharmacokinetic Interaction between Sorafenib and Dapagliflozin in Rats

open access: yesMolecules, 2022
Sorafenib (SOR), an inhibitor of multiple kinases, is a classic targeted drug for advanced hepatocellular carcinoma (HCC) which often coexists with type 2 diabetes mellitus (T2DM). Dapagliflozin (DAPA), a sodium–glucose cotransporter-2 inhibitor (SGLT2i),
Xueru He   +6 more
doaj   +1 more source

Dried Blood Spots—A Platform for Therapeutic Drug Monitoring (TDM) and Drug/Disease Response Monitoring (DRM)

open access: yesEuropean journal of drug metabolism and pharmacokinetics, 2023
This review provides an overview on the current applications of dried blood spots (DBS) as matrices for therapeutic drug (TDM) and drug or disease response monitoring (DRM).
Nur Nabihah Binte Zailani, P. Ho
semanticscholar   +1 more source

Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.

open access: yesTherapeutic Drug Monitoring, 2021
When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy, fixed doses were recommended by the manufacturer. Awareness of the potential for a more personalized dosing has led to development of methods to estimate MPA area under ...
S. Bergan   +37 more
semanticscholar   +1 more source

QiShenYiQi pills, a Chinese patent medicine, increase bioavailability of atorvastatin by inhibiting Mrp2 expression in rats

open access: yesPharmaceutical Biology, 2022
Context Atorvastatin (ATV) and QiShenYiQi pills (QSYQ), a Chinese patent medicine, are often co-prescribed to Chinese cardiovascular patients. The effects of QSYQ on the pharmacokinetics of ATV have not been studied.
Congyang Ding   +8 more
doaj   +1 more source

Pharmacokinetic Interactions between Canagliflozin and Sorafenib or Lenvatinib in Rats

open access: yesMolecules, 2022
Hepatocellular carcinoma (HCC) and type 2 diabetes mellitus (T2DM) are common clinical conditions, and T2DM is an independent risk factor for HCC. Sorafenib and lenvatinib, two multi-targeted tyrosine kinase inhibitors, are first-line therapies for ...
Yanjun Cui   +5 more
doaj   +1 more source

Optimizing Therapies Using Therapeutic Drug Monitoring: Current Strategies and Future Perspectives.

open access: yesGastroenterology, 2022
Therapeutic drug monitoring (TDM) has emerged as a strategy for treatment optimization in inflammatory bowel diseases in order to maximise benefit and to reach more stringent, objective endpoints.
P. Irving, K. Gecse
semanticscholar   +1 more source

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