Results 11 to 20 of about 8,600,526 (387)
Therapeutic drug monitoring—antiepileptic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Aims To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods The review is based on literature data and observations from clinical practice.
M. J. Eadie
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Therapeutic drug monitoring of immunosuppressant drugs [PDF]
British Journal of Clinical Pharmacology, 1999 Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A. E. Johnston, David W. Holt
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Therapeutic drug monitoring: antiarrhythmic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T. J. Campbell, K. M. Williams
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Therapeutic drug monitoring in drug overdose [PDF]
British Journal of Clinical Pharmacology, 1999 The treatment of poisoned patients is still largely defined by history, clinical assessment and interpretation of ancillary investigations. Measurement of drug concentrations is clinically important for relatively few compounds. Most measurements form an adjunct to and should not be considered a substitute for clinical assessment.
Ian M Whyte, Andrew H. Dawson
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Fayixue Zazhi, 2022 ObjectiveTo analyze the chemical structure of the interfering substance that affects the result of methamphetamine analysis in wastewater.MethodsA combination of GC-MS and liquid chromatography-quadrupole time-of-flight mass spectrometry （LC-QTOF-MS） was
ZHANG Ting-ting +4 more
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Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Intensive Care Medicine, 2020 This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill adult patients in the intensive care unit (ICU).
M. Abdul-Aziz +15 more
semanticscholar +1 more source
Determination of five prostaglandin analogs in eyelash enhancing cosmetics by LC-MS/MS
Shanghai yufang yixue, 2022 ObjectiveTo determine bimatoprost， tafluprost ethyl amide， latanoprost， travoprost and tafluprost in eyelash enhancing cosmetics by establishing a LC-MS/MS method.MethodsThe samples were extracted with a 50% acetonitrile water solution. A salt mixture （
XU Yong +4 more
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Mass Fragmentation Characteristics of 4 Synthetic Cathinone Isomers [PDF]
Zhipu Xuebao, 2023 Synthetic cathinones, the designer analogs of the naturally occurring cathinone found in Khat, largely entered the recreational drug market at the end of the 2000s. They are a large class of new psychoactive substances (NPS) often used as substitutes for
JIA Wei;HU Shuang;LI Tao;LIU Cui-mei;WANG You-mei;HUA Zhen-dong
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Monitoring drug adherence [PDF]
Transplantation Reviews, 2015 Medication nonadherence is prevalent in transplant recipients and is a major reason for graft loss. The present review discusses the measurement of adherence in transplant recipients and strategies to improve adherence. SOURCES REVIEWED: Since adherence research is not confined to transplant recipients, our literature review included studies relevant ...
Sarah R. Lieber +5 more
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Therapeutic Drug Monitoring of Ganciclovir: Where Are We?
Therapeutic Drug Monitoring, 2021 Background: Ganciclovir is the mainstay of therapy for the prophylaxis and treatment of Cytomegalovirus. However, therapy with this antiviral agent is hindered by side effects such as myelosuppression, which often leads to therapy cessation. Underdosing,
A. Märtson +6 more
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