Results 61 to 70 of about 1,599,561 (306)
Drug Interactions and Antiretroviral Drug Monitoring [PDF]
Current HIV/AIDS Reports, 2014 Owing to the improved longevity afforded by combination antiretroviral therapy (cART), HIV-infected individuals are developing several non-AIDS-related comorbid conditions. Consequently, medical management of the HIV-infected population is increasingly complex, with a growing list of potential drug-drug interactions (DDIs). This article reviews some of
Matthew, Foy +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Public spending for illegal drug and alcohol treatment in hospitals: an EU cross-country comparison [PDF]
, 2014 Background: In view of the current economic crisis and the resulting austerity measures being implemented by governments across Europe, public expenditure for substance abuse treatment has increasingly become a subject of discussion.
Christiaens, Johan +2 more
core +3 more sources
Fayixue ZazhiObjectiveTo optimize and establish GC-MS, LC-MS, and infrared spectroscopy （IR） methods for analyzing 1-phenyl-2-propanone （P-2-P） and 3,4-methylenedioxyphenyl-2-propanone （MDP-2-P） precursors.MethodsEleven precursor substances of P-2-P and MDP-2-P were ...
LIU Xue-yan +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review
Frontiers in Psychiatry, 2023 BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu +10 more
doaj +1 more source
Therapeutic drug monitoring of immunosuppressant drugs [PDF]
British Journal of Clinical Pharmacology, 1999 Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A, Johnston, D W, Holt
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Medicare Part D: How Do Vulnerable Beneficiaries Fare? [PDF]
, 2008 Based on a survey of counselors, program managers, and health workers, outlines the need to provide user-friendly information, facilitate enrollment and plan choice, and improve monitoring and counseling for the prescription drug benefit's ...
Jeanne Finberg +2 more
core
2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs [PDF]
, 2016 This report represents a scientific and working clinical consensus statement on seizure management in dogs based on current literature and clinical expertise.
Bunch SE +37 more
core +2 more sources