Results 81 to 90 of about 9,044,537 (408)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review

Frontiers in Psychiatry, 2023
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu, Na Xu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +10 more
doaj   +1 more source

Drugs and Crime in Anchorage, Alaska: A Note [PDF]

, 2005
Also published in Alaska Justice Forum 22(1): 7 (Spring 2005).This research note examines the relationship between drug use and offense charged through data collected in 2003 from 259 recent arrestees in Anchorage, Alaska using the Arrestee Drug Abuse ...
Langworthy, Robert H., McKelvie, Alan R.
core  

2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs [PDF]

, 2016
This report represents a scientific and working clinical consensus statement on seizure management in dogs based on current literature and clinical expertise.
Bunch SE, Bunch SE, Cheuk DK, Cunningham JG, Dayrell‐Hart B, Durkes TE, Dyer KR, E.E. Patterson, Farnbach GC, Farnbach GC, Forrester SD, Frey HH, Gaskill CL, Gaskill CL, H.A. Volk, Jacobs G, Jennings PB, K. Muñana, Kantrowitz LB, M. Berendt, M. Podell, March PA, Masuda Y, Nichols ES, Patterson E, Pearce L, Pedersoli WM, Perrucca E, Poffenbarger EM, Ravis WR, S.R. Platt, Schwartz‐Porsche D, Schwartz‐Porsche D, Steinberg M, Thurman GD, Trepanier LA, Trepanier LA, W. Löscher   +37 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors [PDF]

, 2021
Jia‐Yi Long, Hong‐Li Guo, Xin He, Ya‐Hui Hu, Ying Xia, Rui Cheng, Xuansheng Ding, Feng Chen, Jing Xu   +8 more
openalex   +1 more source

Therapeutic drug monitoring of immunosuppressant drugs [PDF]

British Journal of Clinical Pharmacology, 1999
Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A, Johnston, D W, Holt
openaire   +2 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Quantitative Surveys in Hard-to-Reach Populations: The Experience of the ‘Observatoire Français Des Drogues Et Des Toxicomanies’

Methodological Innovations, 2010
This article presents a research device (drawn up by the ‘Observatoire français des drogues et des toxicomanies' or OFDT) for exploring drug consumption practices among ‘hard-to-reach users’.
Agnès Cadet-Taïrou, Catherine Reynaud-Maurupt, Jean-Michel Costes, Christophe Palle   +3 more
doaj   +1 more source

A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire [PDF]

, 2011
Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients.
Christo G., Darke S., Gossop M., Jehanli A., Lundy A., Luty J., M. Uddin, Marsden J., McLellan A. T., Poole W. K., R. Holland, Rosen C. S., Schwartz R. H., Sherman M. F., Simpson D. D., Singleton N., V. Maskrey, Vivancos R.   +17 more
core   +1 more source