Results 121 to 130 of about 78,243 (311)

Laser‐Engraved Print Beds for Creating Bespoke Surface Architectures on Additive Manufactured Electrodes

open access: yesChemElectroChem, EarlyView.
Through laser engraving a pattern onto the print bed of a 3D printer, unique architectures can be produced on additively manufactured electrode surfaces through simply printing onto the pattern with no post‐processing, significantly enhancing the electrochemical performance.
Muhzamil A. Khan   +6 more
wiley   +1 more source

Strategies to Manage Dosing Deviations and Interruptions of Cabotegravir Long‐Acting Intramuscular Injections

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Long‐acting cabotegravir is approved for HIV treatment and prevention. To guide management of dosing deviations and interruptions, concentration‐time profiles for monthly and every 2 months regimens were simulated using a population pharmacokinetic (PPK) model.
Kelong Han   +3 more
wiley   +1 more source

Re‐Evaluation of Fixed Dosing Versus Body Size‐Based Dosing Approaches for Large Molecule Therapeutics in Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Wang et al.1 (2009) and Zhang et al.2 (2011) recommended a fixed dosing approach for large molecule therapeutics for first‐in‐human (FIH) trials, based on the finding that the majority of α values (body size effect on clearance) were < 0.5 across 12 monoclonal antibodies (mAbs) and 18 therapeutic proteins (TPs) and peptides, and fixed dosing provides ...
Andrew B. SyBing   +2 more
wiley   +1 more source

Management of drug overdoses. [PDF]

open access: yesEmergency Medicine Journal, 1996
H. Hughes, A Sen
openaire   +2 more sources

Drug overdose signs and treatment

open access: yes, 2018
Knowing an overdose definition can save lives. We hear a lot in the news about people ending up in the hospital or even dying after taking an overdose of drugs, but what exactly is an overdose? Improve your understanding of what a drug overdose is with this definition, which also includes a review of the common warning signs that a person has consumed ...
openaire   +4 more sources

Identification of the Novel Synthetic Opioid N‐Pyrrolidino Isotonitazene at an Australian Drug Checking Service

open access: yesDrug Testing and Analysis, EarlyView.
Close collaboration between an Australian drug checking service and an affiliated university laboratory identifies and characterises the novel synthetic opioid N‐pyrrolidino isotonitazene in an expected oxycodone sample presented by a member of the public.
Blake Curtis   +3 more
wiley   +1 more source

Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne

open access: yesDrug Testing and Analysis, EarlyView.
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku   +3 more
wiley   +1 more source

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