Results 51 to 60 of about 78,243 (311)
A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim+13 more
wiley +1 more source
An injectable deep eutectic solvent‐based ionic gel is developed for rapid in situ gelation and broad‐spectrum hemostatic functionality. The material combines high mechanical strength, strong tissue adhesion, and antibacterial activity, demonstrating potential as an advanced biofunctional gel for emergency bleeding control and wound care.
Jia‐Yu Yang+13 more
wiley +1 more source
“It wasn’t here, and now it is. It’s everywhere": fentanyl’s rising presence in Oregon’s drug supply
Background Illicit fentanyl has contributed to a drastic increase in overdose drug deaths. While fentanyl has subsumed the drug supply in the Northeastern and Midwestern USA, it has more recently reached the Western USA.
Sarah S. Shin+14 more
doaj +1 more source
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim+8 more
wiley +1 more source
A qualitative study of overdose responses among Chicago IDUs
Background Opioid overdose is a leading cause of death among injection drug users. Over half of injection drug users report at least one nonfatal overdose during their lifetime.
Bigg Dan+5 more
doaj +1 more source
Aims We explored the use of pulverized medication as a new method to prevent intentional drug overdose. Methods This case study presents data obtained from the medical records of two female patients, aged 19 and 27 years, who presented with schizophrenia
Keisuke Takanobu+4 more
doaj +1 more source
Galvanic‐Cell‐Based Self‐Powered Bioelectronic Devices
The emerging galvanic‐cell‐based self‐powered bioelectronics for biomedical applications with passive and active control strategies are summarized. In addition, the challenges and opportunities for galvanic devices are also discussed. Abstract Bioelectronic devices hold significant promise for advancing biomedical technologies, addressing critical ...
Yu Xin+4 more
wiley +1 more source
Drug involvement in fatal overdoses
Death certificate data from the Multiple Cause of Death (MCOD) files were analyzed to better understand the drug categories most responsible for the increase in fatal overdoses occurring between 1999 and 2014. Statistical adjustment methods were used to account for the understatement in reported drug involvement occurring because death certificates ...
openaire +4 more sources
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa+3 more
wiley +1 more source
Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng+4 more
wiley +1 more source