Results 191 to 200 of about 59,924 (341)

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection. [PDF]

Int J Mol Sci
Kosić M, Pajović V, Jovanović M, Japundžić-Žigon N.   +3 more
europepmc   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

Small Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang, Yifan Ma, Yutong Liu, Shiyan Dong, Michelle Najarro Torres, Betty Y.S. Kim, Changsheng Liu, Lili Sun, Yuan Yuan, Wen Jiang   +9 more
wiley   +1 more source

Computational drug repositioning approach to predict multi-target therapeutics for epilepsy. [PDF]

Sci Rep
Kumar P, Kumar V, Chauhan R, Saini V, Kumar A.   +4 more
europepmc   +1 more source

Peer Review #3 of "Mining integrated semantic networks for drug repositioning opportunities (v0.1)"

, 2016
Joseph Mullen, Simon Cockell, Hannah Tipney, Peter Woollard, Anil Wipat, J Alvarsson, M Eklund, O Engkvist, O Spjuth, L Carlsson, J Wikberg, T Noeske, A Bauer-Mehren, M Rautschka, F Sanz, L Furlong, N Betzler, R Van Bevern, M Fellows, C Komusiewicz, R Niedermeier, S Bull, A Doig, J Chambers, M Davies, A Gaulton, A Hersey, S Velankar, R Petryszak, J Hastings, L Bellis, S Mcglinchey, J Overington, B Chen, Y Ding, D Wild, S Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, D Wilkinson, M Young, A Wipat, D Conte, P Foggia, C Sansone, M Vento, L Cordella, P Foggia, C Sansone, M Vento, L Cordella, P Foggia, C Sansone, M Vento, E Dijkstra, H Ding, I Takigawa, H Mamitsuka, S Zhu, S Djoko, D Cook, L Holder, J Dudley, T Deshpande, A Butte, A Escayg, A Goldin, S Fakhraei, B Huang, L Raschid, L Getoor, B Gallagher, R Giugno, D Shasha, M Gobbo, M Louz, B He, J Tang, Y Ding, H Wang, Y Sun, J Shin, B Chen, G Moorthy, J Qiu, P Desai, D Wild, B Holm, M Sehested, P Jensen, M Hurle, L Yang, Q Xie, D Rajpal, P Sanseau, P Agarwal, M Iskar   +99 more
openalex   +2 more sources

Comparing isoflurane and desflurane: A prospective randomised blinded clinical trial in horses undergoing elective surgery

Veterinary Record, EarlyView.
Abstract Background The recovery period is associated with the greatest risk of injury for horses undergoing anaesthesia. Recovery quality and duration can be influenced by the volatile agent. Methods This prospective, randomised blinded clinical investigation recruited 101 healthy client‐owned horses undergoing elective surgery at one UK equine ...
Kate White, John Hird, Polly Taylor
wiley   +1 more source

Integrating population-level and cell-based signatures for drug repositioning. [PDF]

Bioinformatics
He C, Xu Y, Zhou Y, Fan J, Cheng C, Meng R, Wu L, Pan R, Shah RV, Gamazon ER, Zhou D.   +10 more
europepmc   +1 more source

Long‐Term Results of UPPP and Coblation Channeling of the Tongue for Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the long‐term surgical outcomes of combined uvulopalatopharyngoplasty (UPPP) and coblation channeling of the tongue (CCT) for moderate‐to‐severe obstructive sleep apnea (OSA). Methods The study enrolled patients with moderate‐to‐severe OSA who underwent treatment with UPPP plus CCT and had a minimal follow‐up of 2 years ...
Ren‐Hui Chen, Qian Cai, Wei‐Qi Chen, Xiao‐Ming Huang   +3 more
wiley   +1 more source

SIMD: Synergistic integration mutualistic platform based on single-cell and proteotranscriptomics for drug repositioning. [PDF]

NPJ Breast Cancer
Lee SY, Song MY, Lee YR, An JH.
europepmc   +1 more source

Epiglottis Collapse in Individuals With Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated upper airway collapse during sleep. The epiglottis, often overlooked in conventional assessments, has emerged as a site of significant obstruction in OSA.
Dan Chen, Li Zhou, Qi‐Ying Zeng, Yu‐Yin Liu, Jia‐Jing Yang, Rui Liu, Zhi‐Hang Zhou, Fei‐Fei Chen, Li Tang, Fang‐Qi Liang, Hong‐Liang Yi, Su‐Ru Liu   +11 more
wiley   +1 more source