Results 261 to 270 of about 26,660 (305)

Care of Older Adults as Nursing's Defining Ground: Leading the Transformation Toward Prevention‐Focused and Autonomy‐Promoting Healthcare Systems

Journal of Advanced Nursing, EarlyView.
José Manuel Hernández‐Padilla
wiley   +1 more source

In Silico Investigation of TATA-Binding Protein as a Therapeutic Target for Chagas Disease: Insights into FDA Drug Repositioning. [PDF]

Pharmaceuticals (Basel)
Gaona-López C, Méndez-Álvarez D, Gonzalez-Gonzalez A, Avalos-Navarro G, Paz-González AD, Moreno-Rodríguez A, Nogueda-Torres B, Rivera G.   +7 more
europepmc   +1 more source

Repositioning Drugs for Psychiatry.

Avicenna journal of medical biotechnology
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Drug Repositioning in Oncology

American Journal of Therapeutics, 2021
Background: The worldwide increase in the occurrence of cancer associated with the limitations of immunotherapy and the emergence of resistance have impaired the prognosis of cancer patients, which leads to the search for alternative treatment methods.
Marissa B, Serafin, Angelita, Bottega, Taciéli F, da Rosa, Catrine S, Machado, Vitória S, Foletto, Silvana S, Coelho, Augusto D, da Mota, Rosmari, Hörner   +7 more
openaire   +2 more sources

Off-Patent Drug Repositioning

Journal of Chemical Information and Modeling, 2020
Drug repositioning aims to reuse "old" drugs to treat diseases outside their approved indication(s). Composition-of-matter patents and FDA exclusivities can hinder the immediate availability of some drugs to be repositioned (repurposed). Here, we analyze data from the FDA Orange Book and use current on-market patent validity and exclusivities to ...
Sorin Avram, Ramona Curpan, Liliana Halip, Alina Bora, Tudor I. Oprea   +4 more
openaire   +3 more sources

Network-based drug repositioning

Molecular BioSystems, 2013
Network-based computational biology, with the emphasis on biomolecular interactions and omics-data integration, has had success in drug development and created new directions such as drug repositioning and drug combination. Drug repositioning, i.e., revealing a drug's new roles, is increasingly attracting much attention from the pharmaceutical ...
Zikai, Wu, Yong, Wang, Luonan, Chen
openaire   +2 more sources

Drug repositioning for Alzheimer's disease

Nature Reviews Drug Discovery, 2012
Existing drugs for Alzheimer's disease provide symptomatic benefit for up to 12 months, but there are no approved disease-modifying therapies. Given the recent failures of various novel disease-modifying therapies in clinical trials, a complementary strategy based on repositioning drugs that are approved for other indications could be attractive ...
Corbett, Anne, Pickett, James, Burns, Alistair, Corcoran, Jonathan, Dunnett, Stephen B, Edison, Paul, Hagan, Jim J, Holmes, Clive, Jones, Emma, Katona, Cornelius, Kearns, Ian, Kehoe, Patrick, Mudher, Amrit, Passmore, Anthony, Shepherd, Nicola, Walsh, Frank, Ballard, Clive, Passmore, Peter   +17 more
openaire   +4 more sources

Network‐Based Approaches for Drug Repositioning

Molecular Informatics, 2021
AbstractWith deep learning creeping up into the ranks of big data, new models based on deep learning and massive data have made great leaps forward rapidly in the field of drug repositioning. However, there is no relevant review to summarize the transformations and development process of models and their data in the field of drug repositioning.
Tao Song, Gan Wang, Mao Ding, Alfonso Rodriguez‐Paton, Xun Wang, Shudong Wang   +5 more
openaire   +2 more sources

Drug Repositioning on the Cloud

2011 IEEE Third International Conference on Cloud Computing Technology and Science, 2011
Market pressures have driven pharmaceutical companies to reassess their current drug development model and reach out to new innovative business models such as drug repositioning. Various techniques that are used in drug repositioning lend themselves to the distributed computing model. The \cloud is one such computing model that optimizes resource usage
Virvilis V., Sharma A., Koutsokeras M.
openaire   +1 more source

Drug Repositioning Through Network Pharmacology

Current Topics in Medicinal Chemistry, 2016
Low drug productivity has been a significant problem of the pharmaceutical industry for several decades even though numerous novel technologies were introduced during this period. Currently pharmacologic dogma, "single drug, single target, single disease", is at the root of the lack of drug productivity.
Hao, Ye, Jia, Wei, Kailin, Tang, Ritchie, Feuers, Huixiao, Hong   +4 more
openaire   +2 more sources