Results 21 to 30 of about 59,924 (341)
Frontiers in Oncology, 2022 BK002 consists of Achyranthes japonica Nakai (AJN) and Melandrium firmum Rohrbach (MFR) that have been used as herbal medicines in China and Korea. AJN and MFR have been reported to have anti-inflammatory, anti-oxidative, and anti-cancer activities ...
Moon Nyeo Park +17 more
doaj +1 more source
A brief overview of current drug repurposing approaches for COVID-19 management [PDF]
, 2020 This brief overview is intended to shed light on the current drug repositioning (also called drug repurposing) in the therapeutics of the novel coronavirus disease which emerged in 2019 (COVID-19).
Rodrigues, Pedro da Fonseca Soares +1 more
core +2 more sources
Transcriptome-Guided Drug Repositioning [PDF]
Pharmaceutics, 2019 Drug repositioning can save considerable time and resources and significantly speed up the drug development process. The increasing availability of drug action and disease-associated transcriptome data makes it an attractive source for repositioning studies.
Arsen Arakelyan +7 more
openaire +3 more sources
Drug target gene-based analyses of drug repositionability in rare and intractable diseases
Scientific Reports, 2021 Drug development for rare and intractable diseases has been challenging for decades due to the low prevalence and insufficient information on these diseases. Drug repositioning is increasingly being used as a promising option in drug development.
Ryuichi Sakate, Tomonori Kimura
doaj +1 more source
Journal of Cheminformatics, 2020 Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the pre-clinical process of developing
Tamer N. Jarada +2 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2020 Drug repositioning aims to find new indications for existing drugs in order to reduce drug development cost and time. Currently,there are numerous stories of successful drug repositioning that have been reported and many repurposed drugs are already ...
Daniele Parisi +5 more
doaj +1 more source
Journal of Pharmaceutical Policy and Practice, 2020 Drug repositioning is the scientific strategy of investigating existing drugs for additional clinical indications. The advantages of drug repositioning are that it benefits patients and that it adds new indications to existing drugs for lower costs ...
A. B. Bayoumy +4 more
doaj +1 more source
A drug repositioning algorithm based on a deep autoencoder and adaptive fusion
BMC Bioinformatics, 2021 Background Drug repositioning has caught the attention of scholars at home and abroad due to its effective reduction of the development cost and time of new drugs.
Peng Chen +3 more
doaj +1 more source
Drug-Repositioning Approaches Based on Medical and Life Science Databases
Frontiers in Pharmacology, 2021 Drug repositioning is a drug discovery strategy in which an existing drug is utilized as a therapeutic agent for a different disease. As information regarding the safety, pharmacokinetics, and formulation of existing drugs is already available, the cost ...
Yoshito Zamami +10 more
doaj +1 more source
Drug repositioning: A bibliometric analysis
Frontiers in Pharmacology, 2022 Drug repurposing has become an effective approach to drug discovery, as it offers a new way to explore drugs. Based on the Science Citation Index Expanded (SCI-E) and Social Sciences Citation Index (SSCI) databases of the Web of Science core collection, this study presents a bibliometric analysis of drug repurposing publications from 2010 to 2020. Data
Guojun Sun +9 more
openaire +3 more sources