Results 11 to 20 of about 1,936,479 (187)
Network mirroring for drug repositioning [PDF]
BMC Medical Informatics and Decision Making, 2017 Background Although drug discoveries can provide meaningful insights and significant enhancements in pharmaceutical field, the longevity and cost that it takes can be extensive where the success rate is low.
Sunghong Park +2 more
doaj +6 more sources
Drug repositioning in drug discovery of T2DM and repositioning potential of antidiabetic agents
Computational and Structural Biotechnology Journal, 2022 Repositioning or repurposing drugs account for a substantial part of entering approval pipeline drugs, which indicates that drug repositioning has huge market potential and value.
Sha Zhu +3 more
doaj +3 more sources
Transcriptome-Guided Drug Repositioning [PDF]
Pharmaceutics, 2019 Drug repositioning can save considerable time and resources and significantly speed up the drug development process. The increasing availability of drug action and disease-associated transcriptome data makes it an attractive source for repositioning ...
Lilit Nersisyan +7 more
core +4 more sources
Biomedicines, 2023 Drug repositioning offers the significant advantage of greatly reducing the cost and time of drug discovery by identifying new therapeutic indications for existing drugs.
Yoonbee Kim, Young-Rae Cho
doaj +2 more sources
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions [PDF]
Journal of Cheminformatics, 2020 Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the pre-clinical process of developing
Tamer N. Jarada +2 more
doaj +2 more sources
An in silico drug repositioning workflow for host-based antivirals
STAR Protocols, 2021 Summary: Drug repositioning represents a cost- and time-efficient strategy for drug development. Artificial intelligence-based algorithms have been applied in drug repositioning by predicting drug-target interactions in an efficient and high throughput ...
Zexu Li +4 more
doaj +2 more sources
BMC Bioinformatics, 2018 Background Drug repositioning is the process of identifying new uses for existing drugs. Computational drug repositioning methods can reduce the time, costs and risks of drug development by automating the analysis of the relationships in pharmacology ...
Pathima Nusrath Hameed +3 more
doaj +2 more sources
Drug Repositioning in Friedreich Ataxia [PDF]
Frontiers in Neuroscience, 2022 Friedreich ataxia is a rare neurodegenerative disorder caused by insufficient levels of the essential mitochondrial protein frataxin. It is a severely debilitating disease that significantly impacts the quality of life of affected patients and reduces ...
Alessandra Rufini +6 more
doaj +4 more sources
Drug repositioning for schistosomiasis
, 2014 Poster about the project in drug repositioning applied to schistosomiasis carried out at the London School of Hygiene and Tropical Medicine under the supervision of Dr Nick Furnham. Shows preliminary results obtained from the project.
Sandra Giuliani (537795)
core +2 more sources
Drug Repositioning Using Temporal Trajectories of Accompanying Comorbidities in Diabetes Mellitus [PDF]
Endocrinology and Metabolism, 2022 Background Most studies of systematic drug repositioning have used drug-oriented data such as chemical structures, gene expression patterns, and adverse effect profiles.
Namgi Park +4 more
doaj +1 more source