Results 171 to 180 of about 82,231 (299)

Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

British Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman, Laura Buggiotti, Li‐An K. Brown, Jose A. Guerra‐Assuncao, Japhette E. Kembou‐Ringert, Wen Y. Mak, Judith Breuer, David M. Lowe, Joseph F. Standing, FLARE Investigators   +9 more
wiley   +1 more source

m5C: Novel Diagnostic and Drug Repurposing Targets for Nonalcoholic Steatohepatitis. [PDF]

Int J Genomics
Chen S, Duan R, Qiu J, Lei Z, Chen W, Li X.   +5 more
europepmc   +1 more source

Anesthetic Drug Repurposing

Bali Journal of Anesthesiology, 2021
Jasvinder Kaur Kohli, Rohan Magoon, Iti Shri, Ramesh Chand Kashav   +3 more
openaire   +2 more sources

‘When joy comes your way, you have to grab it!’ Troubling how queer joy features in the lives of LGBT+ school‐attending youth in South Africa

British Educational Research Journal, EarlyView.
Abstract Recently, the concept ‘queer joy’ has gained interest in LGBT+ scholarship in the West. I use this scholarship as an entry point to explore how school‐attending LGBT+ youth express joy and how joy serves as a form of resistance against gender and sexuality norms in educational settings.
Dennis Francis
wiley   +1 more source

Correction: Editorial: Opportunities and challenges in drug repurposing. [PDF]

Front Pharmacol
Camps I, Künzel SR, Schubert M, Singh RK.   +3 more
europepmc   +1 more source

More Than 10 Years on: Does a State‐of‐the‐Art Review and Synthesis Offer New Frameworks to Guide Future Design for Remanufacturing Research?

Business Strategy and the Environment, EarlyView.
ABSTRACT There is strong evidence that design for remanufacturing (DfRem) can reduce initial‐design carbon emissions by up to 30%, and that product design can critically affect remanufacturing feasibility, yet academic adoption of DfRem remains limited.
Okechukwu Okorie, Yogendra Singh, Jennifer Russell, Chris Turner, Kingsley Oturu   +4 more
wiley   +1 more source

AΙ-Driven Drug Repurposing: Applications and Challenges. [PDF]

Medicines (Basel)
Keramida P, Syrigos NK, Kouvela M, Poulakou G, Charpidou A, Fiste O.   +5 more
europepmc   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Impact of drug repurposing between 1985 and 2024 on pharmaceutical innovation. [PDF]

Commun Med (Lond)
Akodad S, Niu X, Secades B, Stevens H.
europepmc   +1 more source

Goal Displacement and Goal Conflicts in Circular Innovation Initiatives: Types and Mitigation Practices

Business Strategy and the Environment, EarlyView.
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim, Johan Frishammar, Debadrita Panda   +2 more
wiley   +1 more source