Results 201 to 210 of about 3,841,835 (347)

Challenges and opportunities for oncology drug repurposing informed by synthetic lethality. [PDF]

NPJ Syst Biol Appl
Vermeulen M, Craig AW, Babak T.
europepmc   +1 more source

Artificial intelligence and machine learning‐assisted digital applications for biopharmaceutical manufacturing

Biotechnology Progress, EarlyView.
Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley   +1 more source

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

Clinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller, Peter Douglas, Julie Glen, Emma Aitken   +3 more
wiley   +1 more source

Prompt-based multimodal representation learning for drug repurposing. [PDF]

Brief Bioinform
Liu J, U K, Rana D, Meixuan Zhang S, Yu J, Yang S, Jin B, Wang X, Yang Z, Tang H, Zhao J.   +10 more
europepmc   +1 more source

The Application of Carbon Dots in Crops for Sustainable Agriculture

ChemistryEurope, EarlyView.
Carbon dots serve as versatile nanoagents across the crop life cycle. They promote plant growth and photosynthesis, enhance resilience to biotic and abiotic stresses, aid in postharvest preservation, and enable sensitive detection of contaminants.
Xue Li, Lei Jin, Gurpreet Singh Selopal, Federico Rosei, Jinhua Li   +4 more
wiley   +1 more source

Targetable pathways for drug repurposing in gastric cancer. [PDF]

World J Gastroenterol
Valero-Almingol A, Montori S, Felípez N, Santamaría E, Fernandez-Irigoyen J, Luzko I, Cuestas AA, Pardo C, Prat R, Moreira L, Albéniz E.   +10 more
europepmc   +1 more source

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, EarlyView.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Tumor relapse-free survival prognosis related consistency between cancer tissue and adjacent normal tissue in drug repurposing for solid tumor via connectivity map [PDF]

Mingyue Hao, Dandan Li, Yuanyuan Qiao, Ming Xiong, Jun Li, Wei Ma   +5 more
openalex   +1 more source

On the Influence of Catalyst Mesopore Structure in the Catalytic Cracking of Polypropylene

ChemistryEurope, EarlyView.
Catalytic cracking is a promising approach to convert polyolefin plastics into hydrocarbons. Herein, the effect of catalyst pore size in polypropylene cracking using amorphous silica–alumina with identical external acidity, but varying mesopore diameters and particle sizes, is isolated. Mesopore size has minimal effect on activity, indicating that high
Sebastian Rejman, Tim Meijer, Hamid Seyed Khabbaz, Ali Gooneie, Adriaan J. A. Duijndam, Johan H. van de Minkelis, Ina Vollmer, Bert M. Weckhuysen   +7 more
wiley   +1 more source

Exploiting similarity in drug molecular effects for drug repurposing. [PDF]

Hum Genomics
Huang K, Lalagkas PN, Sultan B, Melamed R.   +3 more
europepmc   +1 more source