Results 11 to 20 of about 1,013,456 (328)

Interplay in the selection of fluoroquinolone resistance and bacterial fitness. [PDF]

PLoS Pathogens, 2009
Fluoroquinolones are antibacterial drugs that inhibit DNA Gyrase and Topoisomerase IV. These essential enzymes facilitate chromosome replication and RNA transcription by regulating chromosome supercoiling.
Linda L Marcusson, Niels Frimodt-Møller, Diarmaid Hughes   +2 more
doaj   +6 more sources

Challenges of Multidrug-resistant New Delhi Metallo-beta-Lactamase (NDM-1)-producing Enterobacteriaceae in Kidney Transplant Patients

Brazilian Journal of Nephrology, 2021
Background: The emergence of multidrug-resistant NDM-1-producing enterobacteriaceae strains has become a threat to inpatients, especially to immunosuppressed ones, such as kidney transplant recipients.
Renato Demarchi Foresto, Lucas Marengo Menezes, Laura Tomoko Nishimura, Marina Pontello Cristelli, Laila Almeida Viana, Daniel Wagner de Castro Lima Santos, Lúcio R. Requião-Moura, Helio Tedesco-Silva, Jose Medina-Pestana   +8 more
doaj   +2 more sources

Multi-drug resistant gram-negative bacterial pneumonia: etiology, risk factors, and drug resistance patterns

Pneumonia, 2022
Bacterial pneumonia is one of the most serious public health issues owing to its medical and economic costs, which result in increased morbidity and mortality in people of all ages around the world.
M. Assefa
semanticscholar   +1 more source

State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review

Antibiotics, 2022
Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and
Hélène Meier, Keira Spinner, Lisa Crump, Esther Kuenzli, Gertraud Schuepbach, Jakob Zinsstag   +5 more
doaj   +1 more source

The Integration of Proteomics and Metabolomics Data Paving the Way for a Better Understanding of the Mechanisms Underlying Microbial Acquired Drug Resistance

Frontiers in Medicine, 2022
Due to an increase in the overuse of antimicrobials and accelerated incidence of drug resistant pathogens, antimicrobial resistance has become a global health threat.
Suereta Fortuin, Nelson C. Soares, Nelson C. Soares   +2 more
doaj   +1 more source

Co-expression of 16S rRNA Methyltransferase and Carbapenemase in Multidrug Resistant Gram Negative Bacteria [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: The drug resistance caused by bacteria has complicated the fight against the infectious diseases and recovery of the patients from the diseases.
Sandeep Kumar Tipparthi, Swathi Akula, HRV Rajkumar, A Ravishankar Reddy, Guru Prasad Manderwad   +4 more
doaj   +1 more source

Catheter-Associated Urinary Tract Infection: Incidence, Associated Factors and Drug Resistance Patterns of Bacterial Isolates in Southern Ethiopia

Infection and Drug Resistance, 2021
Introduction Catheter-associated urinary tract infections (CAUTIs) are the most common nosocomial infection and a leading cause of morbidity. The aim of this study was to determine the prevalence, associated factors and antibiogram of the bacterial ...
Yisiak Oumer, Belayneh Regasa Dadi, M. Seid, Gelila Biresaw, A. Manilal   +4 more
semanticscholar   +1 more source

Non-toxigenic Corynebacterium diphtheriae in hallux ulceration

Journal of Infection in Developing Countries, 2022
Introduction: Toxigenic Corynebacterium diphtheriae causes classical diphtheria. Skin infections by toxigenic or non-toxigenic Corynebacterium diphtheriae are prevalent in the tropics but are rarely reported.
Gauthier Delvallez, Edgar Badell, Sokleaph Cheng, Soda Meng, Vivandet Tong, Judy Norman, Julie Toubiana, Koen Vandelannoote, Anne-Laure Bañuls, Mallorie Hide, Sylvain Brisse   +10 more
doaj   +1 more source

Resisting Bacterial Drug Resistance [PDF]

Chemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire   +3 more sources

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources