Modeling bacterial resistance to antibiotics: bacterial conjugation and drug effects [PDF]
Antibiotic resistance is a major burden in many hospital settings as it drastically reduces the successful probability of treating bacterial infections.
Pirommas Techitnutsarut, Farida Chamchod
doaj +2 more sources
Co-expression of 16S rRNA Methyltransferase and Carbapenemase in Multidrug Resistant Gram Negative Bacteria [PDF]
Introduction: The drug resistance caused by bacteria has complicated the fight against the infectious diseases and recovery of the patients from the diseases.
Sandeep Kumar Tipparthi +4 more
doaj +1 more source
The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile +41 more
core +3 more sources
Resisting Bacterial Drug Resistance [PDF]
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire +2 more sources
Non-toxigenic Corynebacterium diphtheriae in hallux ulceration
Introduction: Toxigenic Corynebacterium diphtheriae causes classical diphtheria. Skin infections by toxigenic or non-toxigenic Corynebacterium diphtheriae are prevalent in the tropics but are rarely reported.
Gauthier Delvallez +10 more
doaj +1 more source
Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne +9 more
core +4 more sources
Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials ...
Hidetada Hirakawa +4 more
doaj +1 more source
Potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida: Comparison of growth media [PDF]
Pharmacodynamic properties of marbofloxacin were established for six isolates each of the pig respiratory tract pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida.
Dorey, L, Hobson, S, Lees, P
core +2 more sources
Pathogens and drug resistance in bacterial diarrhea in Lishui City from 2015 to 2019
ObjectiveTo determine the pathogens and drug resistance in patients with bacterial diarrhea in Lishui City of Zhejiang Province from 2015 to 2019, and provide scientific evidence for prevention and treatment of bacterial diarrhea.MethodFecal specimens ...
ZHANG Qiang +4 more
doaj +1 more source
Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown +27 more
core +2 more sources

