Results 11 to 20 of about 592,323 (309)

Veterinary Medicine Needs New Green Antimicrobial Drugs [PDF]

, 2016
Given that: (1) the worldwide consumption of antimicrobial drugs (AMDs) used in food-producing animals will increase over the coming decades; (2) the prudent use of AMDs will not suffice to stem the rise in human antimicrobial resistance (AMR) of animal ...
Adams, Aidara-Kane, Alvarez, Amidon, Andersson, Andremont, Andremont, Angulo, Ashbolt, Baquero, Bednorz, Bibbal, Bonomo, Brunton, Call, Centers for Disease Control and Prevention, Chantziaras, Chen, Cheng, Cheng, Collignon, DANMAP, de Jong, Dewulf, Duse, Dutil, Edlung, European Food Safety Authority, European Food Safety Authority, European Food Safety Authority, European Medicine Agency, European Medicines Agency, European Medicines Agency, Fairbrother, Food and Drug Administration, Foster, Hansen, Herrick, Heuer, Hofmann, Hojberg, Holman, Horowitz, Huang, Ito, Jacobsen, Kusama, Langlois, Lindecrona, Lipinski, Lipinski, Luo, Marshall, Metz, Midtlyng, Montanari, Naess, Nielsen, Nord, O’Brien, O’Connor, Panagiotidis, Phillips, Pijpers, Pollet, Rashid, Rashid, Ratz, Rioux, Roof, Rose, Sakaeda, Sarmah, Singer, Smith, Sparo, Stamey, Subbiah, Takenouchi, Taverne, Thiele-Bruhn, Tolls, Toutain, Toutain, Toutain, Toutain, Toutain, Trobos, Van Boeckel, van den Bogaard, van der Waaij, Wellington, Whitman, World Health Organisation, World Health Organisation, Yazdankhah, Yusof, Zhang   +97 more
core   +8 more sources

Modeling bacterial resistance to antibiotics: bacterial conjugation and drug effects

Advances in Difference Equations, 2021
Antibiotic resistance is a major burden in many hospital settings as it drastically reduces the successful probability of treating bacterial infections.
Pirommas Techitnutsarut, Farida Chamchod
doaj   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]

, 2015
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne, Ahmad, Amais, Christiansen, Lasse Engbo, Damborg, Peter, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +9 more
core   +4 more sources

Resisting Bacterial Drug Resistance [PDF]

Chemistry & Biology, 2003
In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire   +2 more sources

Non-toxigenic Corynebacterium diphtheriae in hallux ulceration

Journal of Infection in Developing Countries, 2022
Introduction: Toxigenic Corynebacterium diphtheriae causes classical diphtheria. Skin infections by toxigenic or non-toxigenic Corynebacterium diphtheriae are prevalent in the tropics but are rarely reported.
Gauthier Delvallez, Edgar Badell, Sokleaph Cheng, Soda Meng, Vivandet Tong, Judy Norman, Julie Toubiana, Koen Vandelannoote, Anne-Laure Bañuls, Mallorie Hide, Sylvain Brisse   +10 more
doaj   +1 more source

Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter

Frontiers in Microbiology, 2018
Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials ...
Hidetada Hirakawa, Kumiko Kurabayashi, Koichi Tanimoto, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]

, 2016
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais, Christiansen, Lasse Engbo, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +7 more
core   +4 more sources

Classification of Clinical Isolates of Klebsiella pneumoniae Based on Their in vitro Biofilm Forming Capabilities and Elucidation of the Biofilm Matrix Chemistry With Special Reference to the Protein Content

Frontiers in Microbiology, 2019
Klebsiella pneumoniae is a human pathogen, capable of forming biofilms on abiotic and biotic surfaces. The limitations of the therapeutic options against Klebsiella pneumoniae is actually due to its innate capabilities to form biofilm and harboring ...
Ashish Kumar Singh, Ashish Kumar Singh, Shivangi Yadav, Brijesh Singh Chauhan, Nabarun Nandy, Rajan Singh, Kaushik Neogi, Jagat Kumar Roy, Saripella Srikrishna, Rakesh Kumar Singh, Pradyot Prakash   +10 more
doaj   +1 more source

Antibiotic resistance in ocular bacterial infections: an integrative review of ophthalmic chloramphenicol

Tropical Medicine and Health, 2023
Introduction Chloramphenicol is a broad-spectrum antibiotic widely used for treating ophthalmic infections, but concerns about rising bacterial resistance to chloramphenicol have been observed due to its frequent use as an over-the-counter medication ...
Babatunde Ismail Bale, Emmanuel Ebuka Elebesunu, Pirakalai Manikavasagar, Favour Obianuju Agwuna, Isaac Olushola Ogunkola, Alhaji Umar Sow, Don Eliseo Lucero-Prisno   +6 more
doaj   +1 more source