Results 11 to 20 of about 237,994 (265)

Multiple-Replicon Resistance Plasmids of Klebsiella Mediate Extensive Dissemination of Antimicrobial Genes

open access: yesFrontiers in Microbiology, 2021
Multiple-replicon resistance plasmids have become important carriers of resistance genes in Gram-negative bacteria, and the evolution of multiple-replicon plasmids is still not clear.
Xue Wang   +15 more
doaj   +1 more source

The evolution of resistance to synergistic multi‐drug combinations is more complex than evolving resistance to each individual drug component

open access: yesEvolutionary Applications, 2023
Multidrug antibiotic resistance is an urgent public health concern. Multiple strategies have been suggested to alleviate this problem, including the use of antibiotic combinations and cyclic therapies.
Natalie Ann Lozano‐Huntelman   +11 more
doaj   +1 more source

Origin and Dynamics of Mycobacterium tuberculosis Subpopulations That Predictably Generate Drug Tolerance and Resistance

open access: yesmBio, 2022
Initial responses to tuberculosis treatment are poor predictors of final therapeutic outcomes in drug-susceptible disease, suggesting that treatment success depends on features that are hidden within a small minority of the overall infecting ...
Jees Sebastian   +8 more
doaj   +1 more source

Multiple drug resistance bacterial isolates and associated factors among urinary stone patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia [PDF]

open access: yesBMC Urology, 2021
Abstract Background The urinary stone and urinary tract infection (UTI) are invariably associated and are frequent causes of morbidity. Date on burden of UTI among urinary stone patients is lacking in Ethiopia. This study was aimed to assess bacterial profile, antimicrobial susceptibility and associated factors among ...
Desie Kasew   +4 more
openaire   +3 more sources

Human Multidrug-Resistant Salmonella Newport Infections, Wisconsin, 2003–2005

open access: yesEmerging Infectious Diseases, 2007
We conducted a retrospective study of Salmonella Newport infections among Wisconsin residents during 2003–2005. Multidrug resistance prevalence was substantially greater in Wisconsin than elsewhere in the United States.
Amy E. Karon   +4 more
doaj   +1 more source

Interplay in the selection of fluoroquinolone resistance and bacterial fitness. [PDF]

open access: yesPLoS Pathogens, 2009
Fluoroquinolones are antibacterial drugs that inhibit DNA Gyrase and Topoisomerase IV. These essential enzymes facilitate chromosome replication and RNA transcription by regulating chromosome supercoiling.
Linda L Marcusson   +2 more
doaj   +1 more source

Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens

open access: yeseLife, 2021
The success of antimicrobial treatment is threatened by the evolution of drug resistance. Population genetic models are an important tool in mitigating that threat.
Claudia Igler, Jens Rolff, Roland Regoes
doaj   +1 more source

Etiology of Diarrhoea with Reference to Multiple Drug Resistant Enteric Bacterial Pathogens

open access: yesNepal Journal of Science and Technology, 1970
A total of 340 stool samples were processed and studied from both sexes including all ages of patients. Association of enteropathogens between male and female was not statistically significant. Incidence of diarrhoea (28.23%) as well as prevalence of enteropathogens (34.31%) was found highest in the age group (20-30) years.
Shital Raj Basnyat   +2 more
openaire   +2 more sources

A prospective study of treatment of carbapenem-resistant Enterobacteriaceae infections and risk factors associated with outcome

open access: yesBMC Infectious Diseases, 2016
Background To describe the clinical and microbiological data of carbapenem-resistant Enterobacteriaceae (CRE) infections, the treatment used, hospital- and infection-related mortality, and risk factors for death.
Claudia M. D. de Maio Carrilho   +8 more
doaj   +1 more source

Investigating the Prevalence and Antibiotic Resistance Pattern of Nosocomial Bacterial Infections in Imam Khomeini Hospital, Sari [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Nosocomial infections are considered as a significant problem in medical centers, causing a high mortality rate among hospitalized patients, increasing the duration of hospitalization and treatment costs.
Roya Ghasemian   +2 more
doaj  

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