Results 31 to 40 of about 237,994 (265)

Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis [PDF]

The Korean Journal of Internal Medicine
Background/Aims Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of
Aryoung Kim, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Myung Ji Goh   +8 more
doaj   +1 more source

Identification and Distribution of Pathogens in a Major Tertiary Hospital of Indonesia

Frontiers in Public Health, 2020
The nosocomial persistence of multiple drug resistance organisms constitutes a global threat. Healthcare-setting acquired infections are subject to substantial selection pressure and are frequently associated with drug resistance.
Nyoman Sri Budayanti, Nyoman Sri Budayanti, Dewi N. Aisyah, Dewi N. Aisyah, Nengah N. D. Fatmawati, Nengah N. D. Fatmawati, Ni M. A. Tarini, Ni M. A. Tarini, Zisis Kozlakidis, Zisis Kozlakidis, Wiku Adisasmito   +10 more
doaj   +1 more source

Determination of Duration of the Intensive Phase of Chemotherapy for Respiratory Tuberculosis in Children without Bacterial Excretion and at No Risk of Multiple and Extensive Drug Resistance

Tuberculosis and Lung Diseases, 2021
The objective of the study: to develop criteria to evaluate the duration of the intensive phase of chemotherapy for respiratory tuberculosis in children without bacterial excretion and at no risk of multiple and extensive drug resistance of tuberculous mycobacteria.Subjects and methods. Totally, 93 patients with newly diagnosed respiratory tuberculosis
M. F. Gubkinа, N. V. Yukhimenko, S. S. Sterlikovа, Yu. Yu. Khokhlovа, I. Yu. Petrаkovа   +4 more
openaire   +3 more sources

Complementary supramolecular drug associates in perfecting the multidrug therapy against multidrug resistant bacteria

Frontiers in Immunology
The inappropriate and inconsistent use of antibiotics in combating multidrug-resistant bacteria exacerbates their drug resistance through a few distinct pathways.
Pathik Sahoo, Pathik Sahoo
doaj   +1 more source

Appropriateness of antibiotic therapy in sepsis patients in the intensive care unit: A single-center observational study [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Sepsis remains a major cause of mortality in intensive care units, and antimicrobial selection is complicated by local resistance patterns.
Ha T.T. Dinh, Khoi X. Pham, An N. Nguyen
doaj   +1 more source

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development

mBio, 2020
Antimicrobial resistance is a major health threat as it limits treatment options for infection. At the forefront of this serious issue is Acinetobacter baumannii, a Gram-negative opportunistic pathogen that exhibits the remarkable ability to resist ...
Christopher E. Morgan, Wei Huang, Susan D. Rudin, Derek J. Taylor, James E. Kirby, Robert A. Bonomo, Edward W. Yu   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multilabel hybridization probes for sequence-specific detection of sepsis-related drug resistance genes in plasmids

Talanta Open, 2021
Emerging antimicrobial drug resistance is increasing the complexity involved in treating critical conditions such as bacterial induced sepsis. Methods for diagnosing specific drug resistance tend to be rapid or sensitive, but not both.
Robert L. Hanson, Elaine Lazalde, Radim Knob, David H. Harris, Yesman Akuoko, Jacob B. Nielsen, Adam T. Woolley   +6 more
doaj   +1 more source

Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates

American Journal of BioScience, 2014
Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source