Results 31 to 40 of about 9,006,960 (303)

Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. [PDF]

open access: yes, 2008
BACKGROUND: Human and animal health is constantly under threat by emerging pathogens that have recently acquired genetic determinants that enhance their survival, transmissibility and virulence.
Oyston, Petra C. F.   +38 more
core   +1 more source

Transferable drug resistance plasmids in fish-pathogenic bacteria [PDF]

open access: yes, 2000
Chemotherapeutic agents have been developed for treating bacterial infections and have been widely used for cultured fish for the last 30 years in Japan.
Aoki, Takashi
core   +1 more source

Isolation and characterization of multiple drug resistance bacterial pathogens from waste water in hospital and non-hospital environments, Northwest Ethiopia [PDF]

open access: yesBMC Research Notes, 2014
The importance of bacterial isolates from waste water environment as a reservoir of antibiotic resistance and a potential source of novel resistance genes to clinical pathogens is underestimated. This study is aimed at to isolate and characterize public health important bacteria from waste water in hospital and non- hospital environments and evaluate ...
Moges, Feleke   +3 more
openaire   +3 more sources

Thioredoxin Reductase Is a Valid Target for Antimicrobial Therapeutic Development Against Gram-Positive Bacteria

open access: yesFrontiers in Microbiology, 2021
There is a drought of new antibacterial compounds that exploit novel targets. Thioredoxin reductase (TrxR) from the Gram-positive bacterial antioxidant thioredoxin system has emerged from multiple screening efforts as a potential target for auranofin ...
LewisOscar Felix   +2 more
doaj   +1 more source

Heavy metal tolerance and multiple drug resistance of heterotrophic bacterial isolates from metal contaminated soil [PDF]

open access: yesThe South Pacific Journal of Natural and Applied Sciences, 2013
The development of multiple metal/antibiotic resistances among the bacterial population causes a potential risk to human health. Metal contamination in natural environments could have an important role in the maintenance and proliferation of antibiotic resistance.
M. P. Krishna   +2 more
openaire   +1 more source

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

open access: yes, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S.   +35 more
core   +1 more source

A population model evaluating the consequences of the evolution of double-resistance and tradeoffs on the benefits of two-drug antibiotic treatments. [PDF]

open access: yesPLoS ONE, 2014
The evolution of antibiotic resistance in microbes poses one of the greatest challenges to the management of human health. Because addressing the problem experimentally has been difficult, research on strategies to slow the evolution of resistance ...
Ellsworth M Campbell, Lin Chao
doaj   +1 more source

Genome Recombination-Mediated tRNA Up-Regulation Conducts General Antibiotic Resistance of Bacteria at Early Stage

open access: yesFrontiers in Microbiology, 2022
Bacterial antibiotic resistance sets a great challenge to human health. It seems that the bacteria can spontaneously evolve resistance against any antibiotic within a short time without the horizontal transfer of heterologous genes and before ...
Huiying Fang   +10 more
doaj   +1 more source

Spread of anti-malarial drug resistance: mathematical model with implications for ACT drug policies. [PDF]

open access: yes, 2008
BACKGROUND: Most malaria-endemic countries are implementing a change in anti-malarial drug policy to artemisinin-based combination therapy (ACT). The impact of different drug choices and implementation strategies is uncertain.
Hastings, Ian M   +26 more
core   +1 more source

Multiple drug resistance in bacterial isolates from liquid wastes generated in central hospitals of Nepal

open access: yesKathmandu University Medical Journal, 1970
Background: Healthcare liquid wastes are the reservoirs of harmful infectious agents such as the pathogens and multiple drug resistant microorganisms. Potential infectious risks include the spread of infectious diseases and microbial resistance from health-care establishments into the environment and thereby posing risks of getting infections and ...
D R, Sharma, B, Pradhan, S K, Mishra
openaire   +3 more sources

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