Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]
, 2017 Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina +15 more
core +2 more sources
Heavy metal tolerance and multiple drug resistance of heterotrophic bacterial isolates from metal contaminated soil [PDF]
The South Pacific Journal of Natural and Applied Sciences, 2013 The development of multiple metal/antibiotic resistances among the bacterial population causes a potential risk to human health. Metal contamination in natural environments could have an important role in the maintenance and proliferation of antibiotic resistance.
M. P. Krishna +2 more
openaire +1 more source
Interplay in the selection of fluoroquinolone resistance and bacterial fitness. [PDF]
PLoS Pathogens, 2009 Fluoroquinolones are antibacterial drugs that inhibit DNA Gyrase and Topoisomerase IV. These essential enzymes facilitate chromosome replication and RNA transcription by regulating chromosome supercoiling.
Linda L Marcusson +2 more
doaj +1 more source
Human Multidrug-Resistant Salmonella Newport Infections, Wisconsin, 2003–2005
Emerging Infectious Diseases, 2007 We conducted a retrospective study of Salmonella Newport infections among Wisconsin residents during 2003–2005. Multidrug resistance prevalence was substantially greater in Wisconsin than elsewhere in the United States.
Amy E. Karon +4 more
doaj +1 more source
Investigating the Prevalence and Antibiotic Resistance Pattern of Nosocomial Bacterial Infections in Imam Khomeini Hospital, Sari [PDF]
Journal of Mazandaran University of Medical Sciences, 2023 Background and purpose: Nosocomial infections are considered as a significant problem in medical centers, causing a high mortality rate among hospitalized patients, increasing the duration of hospitalization and treatment costs.
Roya Ghasemian +2 more
doaj
Frontiers in Microbiology, 2021 There is a drought of new antibacterial compounds that exploit novel targets. Thioredoxin reductase (TrxR) from the Gram-positive bacterial antioxidant thioredoxin system has emerged from multiple screening efforts as a potential target for auranofin ...
LewisOscar Felix +2 more
doaj +1 more source
In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection [PDF]
, 2017 Pseudomonas aeruginosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers. Recently, the frog skin-derived antimicrobial peptide (AMP) Esc(1-21) and its diastereomer Esc(1-21)-1c were found to ...
Chen, Chen +2 more
core +1 more source
BMC Infectious Diseases, 2016 Background To describe the clinical and microbiological data of carbapenem-resistant Enterobacteriaceae (CRE) infections, the treatment used, hospital- and infection-related mortality, and risk factors for death.
Claudia M. D. de Maio Carrilho +8 more
doaj +1 more source
A population model evaluating the consequences of the evolution of double-resistance and tradeoffs on the benefits of two-drug antibiotic treatments. [PDF]
PLoS ONE, 2014 The evolution of antibiotic resistance in microbes poses one of the greatest challenges to the management of human health. Because addressing the problem experimentally has been difficult, research on strategies to slow the evolution of resistance ...
Ellsworth M Campbell, Lin Chao
doaj +1 more source
Frontiers in Microbiology, 2022 Bacterial antibiotic resistance sets a great challenge to human health. It seems that the bacteria can spontaneously evolve resistance against any antibiotic within a short time without the horizontal transfer of heterologous genes and before ...
Huiying Fang +10 more
doaj +1 more source