Results 41 to 50 of about 334,672 (303)

In Vitro Efficacy of Imipenem/Relebactam Against Imipenem Resistant Gram-Negative Strains Isolated from a Tertiary Care Hospital

open access: yesPakistan Armed Forces Medical Journal
Objective: To determine in vitro efficacy of Imipenem/Relebactam against multi-drug resistant strains. Study Design: Cross-sectional study. Place and Duration of Study: Department of Microbiology, Fauji Foundation Hospital (FFH) Rawalpindi, Pakistan
Saima Ishtiaq   +5 more
doaj   +1 more source

Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis [PDF]

open access: yesThe Korean Journal of Internal Medicine
Background/Aims Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of
Aryoung Kim   +8 more
doaj   +1 more source

Identification and Distribution of Pathogens in a Major Tertiary Hospital of Indonesia

open access: yesFrontiers in Public Health, 2020
The nosocomial persistence of multiple drug resistance organisms constitutes a global threat. Healthcare-setting acquired infections are subject to substantial selection pressure and are frequently associated with drug resistance.
Nyoman Sri Budayanti   +10 more
doaj   +1 more source

Multilabel hybridization probes for sequence-specific detection of sepsis-related drug resistance genes in plasmids

open access: yesTalanta Open, 2021
Emerging antimicrobial drug resistance is increasing the complexity involved in treating critical conditions such as bacterial induced sepsis. Methods for diagnosing specific drug resistance tend to be rapid or sensitive, but not both.
Robert L. Hanson   +6 more
doaj   +1 more source

tRNA Methylation Is a Global Determinant of Bacterial Multi-Drug Resistance

open access: yesCell Systems, 2019
SUMMARY Gram-negative bacteria are intrinsically resistant to drugs, due to their double-membrane envelope structure that acts as a permeability barrier and as an anchor for efflux pumps.
Isao Masuda   +9 more
semanticscholar   +1 more source

The Mechanism of Bacterial Resistance and Potential Bacteriostatic Strategies

open access: yesAntibiotics, 2022
Bacterial drug resistance is rapidly developing as one of the greatest threats to human health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics according to the antibacterial mechanism of antibiotics, involving ...
Fusheng Zhang, Wei Cheng
semanticscholar   +1 more source

The Utility of Colistin in Multiple Drug-Resistant Pseudomonas aeruginosa Bacterial Keratitis in a Kaposi’s Sarcoma Patient

open access: yesTurkish journal of ophthalmology, 2019
A 71-year-old male patient presented with decreased visual acuity, redness, and discharge in his right eye for 5 days. He had undergone evisceration of his left eye several years earlier. Before presentation, he had received chemotherapeutic agents for Kaposi’s sarcoma of the scalp.
Barut Selver Ö.   +4 more
openaire   +5 more sources

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development

open access: yesmBio, 2020
Antimicrobial resistance is a major health threat as it limits treatment options for infection. At the forefront of this serious issue is Acinetobacter baumannii, a Gram-negative opportunistic pathogen that exhibits the remarkable ability to resist ...
Christopher E. Morgan   +6 more
doaj   +1 more source

Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050

open access: yesThe Lancet
Summary Background Antimicrobial resistance (AMR) poses an important global health challenge in the 21st century. A previous study has quantified the global and regional burden of AMR for 2019, followed with additional publications that provided more ...
M. Naghavi   +499 more
semanticscholar   +1 more source

Ertapebem disk performance to predict Klebsiella pneumoniae carbapenemase produced by Gram-negative bacilli isolated in a São Paulo city public hospital

open access: yesEinstein (São Paulo)
OBJECTIVE: To evaluate ertapenem disk performance to predict Klebsiella pneumonie carbapenemase production by Gram-negative bacilli. METHODS: All Gram-negative bacilli isolated between January 2010 and June 2011 were tested by disk diffusion (OxoidTM ...
Lais Pinto de Almeida   +5 more
doaj   +1 more source

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