Results 21 to 30 of about 237,994 (265)

Thioredoxin Reductase Is a Valid Target for Antimicrobial Therapeutic Development Against Gram-Positive Bacteria

open access: yesFrontiers in Microbiology, 2021
There is a drought of new antibacterial compounds that exploit novel targets. Thioredoxin reductase (TrxR) from the Gram-positive bacterial antioxidant thioredoxin system has emerged from multiple screening efforts as a potential target for auranofin ...
LewisOscar Felix   +2 more
doaj   +1 more source

Isolation and characterization of multiple drug resistance bacterial pathogens from waste water in hospital and non-hospital environments, Northwest Ethiopia [PDF]

open access: yesBMC Research Notes, 2014
The importance of bacterial isolates from waste water environment as a reservoir of antibiotic resistance and a potential source of novel resistance genes to clinical pathogens is underestimated. This study is aimed at to isolate and characterize public health important bacteria from waste water in hospital and non- hospital environments and evaluate ...
Moges, Feleke   +3 more
openaire   +3 more sources

A population model evaluating the consequences of the evolution of double-resistance and tradeoffs on the benefits of two-drug antibiotic treatments. [PDF]

open access: yesPLoS ONE, 2014
The evolution of antibiotic resistance in microbes poses one of the greatest challenges to the management of human health. Because addressing the problem experimentally has been difficult, research on strategies to slow the evolution of resistance ...
Ellsworth M Campbell, Lin Chao
doaj   +1 more source

Genome Recombination-Mediated tRNA Up-Regulation Conducts General Antibiotic Resistance of Bacteria at Early Stage

open access: yesFrontiers in Microbiology, 2022
Bacterial antibiotic resistance sets a great challenge to human health. It seems that the bacteria can spontaneously evolve resistance against any antibiotic within a short time without the horizontal transfer of heterologous genes and before ...
Huiying Fang   +10 more
doaj   +1 more source

Heavy metal tolerance and multiple drug resistance of heterotrophic bacterial isolates from metal contaminated soil [PDF]

open access: yesThe South Pacific Journal of Natural and Applied Sciences, 2013
The development of multiple metal/antibiotic resistances among the bacterial population causes a potential risk to human health. Metal contamination in natural environments could have an important role in the maintenance and proliferation of antibiotic resistance.
M. P. Krishna   +2 more
openaire   +1 more source

Revisión sistemática de la farmacorresistencia en enterobacterias de aislamientos hospitalarios en Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2014
Introducción. La resistencia bacteriana es un problema de salud pública a nivel mundial que compromete seriamente la capacidad de tratar las infecciones. Objetivo.
Leidy González, Jorge Alberto Cortés
doaj   +1 more source

Multiple drug resistance in bacterial isolates from liquid wastes generated in central hospitals of Nepal

open access: yesKathmandu University Medical Journal, 1970
Background: Healthcare liquid wastes are the reservoirs of harmful infectious agents such as the pathogens and multiple drug resistant microorganisms. Potential infectious risks include the spread of infectious diseases and microbial resistance from health-care establishments into the environment and thereby posing risks of getting infections and ...
D R, Sharma, B, Pradhan, S K, Mishra
openaire   +3 more sources

In Vitro Efficacy of Imipenem/Relebactam Against Imipenem Resistant Gram-Negative Strains Isolated from a Tertiary Care Hospital

open access: yesPakistan Armed Forces Medical Journal
Objective: To determine in vitro efficacy of Imipenem/Relebactam against multi-drug resistant strains. Study Design: Cross-sectional study. Place and Duration of Study: Department of Microbiology, Fauji Foundation Hospital (FFH) Rawalpindi, Pakistan
Saima Ishtiaq   +5 more
doaj   +1 more source

The Utility of Colistin in Multiple Drug-Resistant Pseudomonas aeruginosa Bacterial Keratitis in a Kaposi’s Sarcoma Patient

open access: yesTurkish journal of ophthalmology, 2019
A 71-year-old male patient presented with decreased visual acuity, redness, and discharge in his right eye for 5 days. He had undergone evisceration of his left eye several years earlier. Before presentation, he had received chemotherapeutic agents for Kaposi’s sarcoma of the scalp.
Barut Selver Ö.   +4 more
openaire   +5 more sources

Ertapebem disk performance to predict Klebsiella pneumoniae carbapenemase produced by Gram-negative bacilli isolated in a São Paulo city public hospital

open access: yesEinstein (São Paulo)
OBJECTIVE: To evaluate ertapenem disk performance to predict Klebsiella pneumonie carbapenemase production by Gram-negative bacilli. METHODS: All Gram-negative bacilli isolated between January 2010 and June 2011 were tested by disk diffusion (OxoidTM ...
Lais Pinto de Almeida   +5 more
doaj   +1 more source

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