Results 51 to 60 of about 334,672 (303)

Microflora in patients with community-acquired pneumonia and hospital environment in Blagoveshchensk during pandemic

International Journal of Infectious Diseases, 2022
Purpose: An increase of community-acquired pneumonia (CAP) incidence has been detected during COVID-19 pandemic. Aim: to conduct analysis of bacterial microflora isolated from patients suffering from CAP and hospital environment in hospitals.
O. Kurganova, N. Pshenichnaya, E. Burdinskaya, Y. Natykan, O. Trotsenko, A. Bondarenko, V. Shmylenko, E. Bazykina   +7 more
doaj   +1 more source

Antimicrobial Activities of Methanol, Ethanol and Supercritical CO2 Extracts of Philippine Piper betle L. on Clinical Isolates of Gram Positive and Gram Negative Bacteria with Transferable Multiple Drug Resistance

PLoS ONE, 2016
Piper betle L. has traditionally been used in alternative medicine in different countries for various therapeutic purposes, including as an anti-infective agent. However, studies reported in the literature are mainly on its activities on drug susceptible
D. L. Valle, E. Cabrera, J. Puzon, W. Rivera   +3 more
semanticscholar   +1 more source

Determination of Duration of the Intensive Phase of Chemotherapy for Respiratory Tuberculosis in Children without Bacterial Excretion and at No Risk of Multiple and Extensive Drug Resistance

Tuberculosis and Lung Diseases, 2021
The objective of the study: to develop criteria to evaluate the duration of the intensive phase of chemotherapy for respiratory tuberculosis in children without bacterial excretion and at no risk of multiple and extensive drug resistance of tuberculous mycobacteria.Subjects and methods. Totally, 93 patients with newly diagnosed respiratory tuberculosis
M. F. Gubkinа, N. V. Yukhimenko, S. S. Sterlikovа, Yu. Yu. Khokhlovа, I. Yu. Petrаkovа   +4 more
openaire   +3 more sources

Complementary supramolecular drug associates in perfecting the multidrug therapy against multidrug resistant bacteria

Frontiers in Immunology
The inappropriate and inconsistent use of antibiotics in combating multidrug-resistant bacteria exacerbates their drug resistance through a few distinct pathways.
Pathik Sahoo, Pathik Sahoo
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Rate and impact of duodenoscope contamination: A systematic review and meta-analysis

EClinicalMedicine, 2020
Background: Multiple infection outbreaks have been linked to contaminated duodenoscopes worldwide. However, the contamination rate of patient-ready duodenoscopes varies highly amongst published studies testing this subject.
Sara Larsen, Rasmus Vinther Russell, Lotte Klinten Ockert, Stephen Spanos, Helena Strømstad Travis, Lars Holger Ehlers, Anders Mærkedahl   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

EBioMedicine, 2015
Current antibiotic testing does not include the potential influence of host cell environment on microbial susceptibility and antibiotic resistance, hindering appropriate therapeutic intervention.
Jessica Z. Kubicek-Sutherland, Douglas M. Heithoff, Selvi C. Ersoy, William R. Shimp, John K. House, Jamey D. Marth, Jeffrey W. Smith, Michael J. Mahan   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multiple Mechanisms of the Synthesized Antimicrobial Peptide TS against Gram-Negative Bacteria for High Efficacy Antibacterial Action In Vivo

Molecules, 2020
The emergence of drug-resistant bacteria emphasizes the urgent need for novel antibiotics. The antimicrobial peptide TS shows extensive antibacterial activity in vitro and in vivo, especially in gram-negative bacteria; however, its antibacterial ...
Rui Zhang, Xiaobo Fan, Xinglu Jiang, Mingyuan Zou, Han Xiao, Guoqiu Wu   +5 more
doaj   +1 more source