Results 51 to 60 of about 431,274 (302)

The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]

, 2014
Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core   +2 more sources

In Vitro Efficacy of Imipenem/Relebactam Against Imipenem Resistant Gram-Negative Strains Isolated from a Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objective: To determine in vitro efficacy of Imipenem/Relebactam against multi-drug resistant strains. Study Design: Cross-sectional study. Place and Duration of Study: Department of Microbiology, Fauji Foundation Hospital (FFH) Rawalpindi, Pakistan
Saima Ishtiaq, Sonia Tahir, Muhammad Waqas Abbas, Haider Ali, Saima Syed, Fatima Kareem   +5 more
doaj   +1 more source

Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis [PDF]

The Korean Journal of Internal Medicine
Background/Aims Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of
Aryoung Kim, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Myung Ji Goh   +8 more
doaj   +1 more source

Identification and Distribution of Pathogens in a Major Tertiary Hospital of Indonesia

Frontiers in Public Health, 2020
The nosocomial persistence of multiple drug resistance organisms constitutes a global threat. Healthcare-setting acquired infections are subject to substantial selection pressure and are frequently associated with drug resistance.
Nyoman Sri Budayanti, Nyoman Sri Budayanti, Dewi N. Aisyah, Dewi N. Aisyah, Nengah N. D. Fatmawati, Nengah N. D. Fatmawati, Ni M. A. Tarini, Ni M. A. Tarini, Zisis Kozlakidis, Zisis Kozlakidis, Wiku Adisasmito   +10 more
doaj   +1 more source

Genome editing technologies to fight infectious diseases [PDF]

, 2017
Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa, Pal\ue3\ub9, Giorgio, Trevisan, Marta   +2 more
core   +1 more source

Ertapebem disk performance to predict Klebsiella pneumoniae carbapenemase produced by Gram-negative bacilli isolated in a São Paulo city public hospital

Einstein (São Paulo)
OBJECTIVE: To evaluate ertapenem disk performance to predict Klebsiella pneumonie carbapenemase production by Gram-negative bacilli. METHODS: All Gram-negative bacilli isolated between January 2010 and June 2011 were tested by disk diffusion (OxoidTM ...
Lais Pinto de Almeida, Fabiana Puerro de Carvalho, Alexandre Gimenes Marques, Andrea dos Santos Pereira, Renata Puzzo Bortoleto, Marinês Dalla Valle Martino   +5 more
doaj   +1 more source

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development

mBio, 2020
Antimicrobial resistance is a major health threat as it limits treatment options for infection. At the forefront of this serious issue is Acinetobacter baumannii, a Gram-negative opportunistic pathogen that exhibits the remarkable ability to resist ...
Christopher E. Morgan, Wei Huang, Susan D. Rudin, Derek J. Taylor, James E. Kirby, Robert A. Bonomo, Edward W. Yu   +6 more
doaj   +1 more source

Multilabel hybridization probes for sequence-specific detection of sepsis-related drug resistance genes in plasmids

Talanta Open, 2021
Emerging antimicrobial drug resistance is increasing the complexity involved in treating critical conditions such as bacterial induced sepsis. Methods for diagnosing specific drug resistance tend to be rapid or sensitive, but not both.
Robert L. Hanson, Elaine Lazalde, Radim Knob, David H. Harris, Yesman Akuoko, Jacob B. Nielsen, Adam T. Woolley   +6 more
doaj   +1 more source

Microflora in patients with community-acquired pneumonia and hospital environment in Blagoveshchensk during pandemic

International Journal of Infectious Diseases, 2022
Purpose: An increase of community-acquired pneumonia (CAP) incidence has been detected during COVID-19 pandemic. Aim: to conduct analysis of bacterial microflora isolated from patients suffering from CAP and hospital environment in hospitals.
O. Kurganova, N. Pshenichnaya, E. Burdinskaya, Y. Natykan, O. Trotsenko, A. Bondarenko, V. Shmylenko, E. Bazykina   +7 more
doaj   +1 more source

Pneumonia Caused by Klebsiella spp. in 46 Horses. [PDF]

, 2015
BackgroundKlebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression.Hypothesis/objectivesTo describe the signalment, clinicopathologic data, radiographic and ...
Aleman, M, Byrne, BA, Estell, KE, Kass, PH, Kozikowski, T, Reilly, CM, Swain, EA, Young, A   +7 more
core   +1 more source