Results 121 to 130 of about 2,071,500 (370)

The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa [PDF]

, 2010
Background. The Beijing genotype of M. tuberculosis is a virulent strain that is disseminating worldwide and has a strong association with drug resistance.
A Aubry, A Dessen, AD Calver, AE DeBarber, AG Tsolaki, AL Delcher, B Lopez, BJ Marais, C Manca, C Manca, CK Mlambo, D Almeida, D Hillemann, D van Soolingen, DD Anh, Elizabeth M Streicher, EM Streicher, F Drobniewski, F Wang, G Middlebrook, GD van der Spuy, GE Pfyffer, GP Morlock, I Mokrousov, I Parwati, I Parwati, J Felsenstein, J Kamerbeek, J Werngren, James C Sacchettini, JR Glynn, JR Glynn, Karen M Dobos, L Tsenova, LE Via, M Ebrahimi-Rad, M Hanekom, M Mphahlele, M Pillay, M Richardson, M Zhang, MB Reed, MH Larsen, MW Borgdorff, Nicolaas C Gey van Pittius, OJ Strauss, OS Toungoussova, P Constant, Paul D Van Helden, PJ Bifani, PJ Bifani, Q Li, R Johnson, R Johnson, R Johnson, R Warren, RM Warren, Robin M Warren, S Gagneux, S Kurtz, S Ramaswamy, S Sreevatsan, S Sreevatsan, S Sreevatsan, S Sreevatsan, SI Durbach, SJ Cheng, T Dos Vultos, T Iwamoto, TC Victor, Thomas C Victor, Thomas R Ioerger, TR Frieden, TR Ioerger, Xiaohua Chen, Y Suzuki, Yicheng Feng, YK Park   +77 more
core   +4 more sources

Precision Therapeutic Biomarker Identification with Application to the Cancer Genome Project [PDF]

arXiv, 2017
Cancer cell lines have frequently been used to link drug sensitivity and resistance with genomic profiles. To capture genomic complexity in cancer, the Cancer Genome Project (CGP) (Garnett et al., 2012) screened 639 human tumor cell lines with 130 drugs ranging from known chemotherapeutic agents to experimental compounds. Questions of interest include:
arxiv  

AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]

arXiv, 2023
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

EXPERIENCE OF USING THE TB DRUG OF PERCHLOZON IN TUBERCULOSIS PATIENTS WITH MULTIPLE DRUG RESISTANCE IN BURYATIA REPUBLIC

Туберкулез и болезни лёгких, 2015
Lately the main TB epidemiological rates are becoming stable in Buryatia Republic. In 2013-2014 the e¾ciency of use of perchlozon was studied within integral treatment of pulmonary tuberculosis patients with multiple and extensive drug resistance (MDR ...
S. V. Nikolaeva
doaj  

Deep graph embedding for prioritizing synergistic anticancer drug combinations [PDF]

arXiv, 2019
Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and time-consuming to screen all possible drug pairs experimentally.
arxiv  

Isolation and characterization of multiple drug resistance bacterial pathogens from waste water in hospital and non-hospital environments, Northwest Ethiopia

BMC Research Notes, 2014
The importance of bacterial isolates from waste water environment as a reservoir of antibiotic resistance and a potential source of novel resistance genes to clinical pathogens is underestimated.
F. Moges, Mengistu Endris, Yeshambel Belyhun, Walelegn Worku   +3 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Antibiotic Resistance of Vibrio cholerae Isolates from Kashan, Iran

International Archives of Health Sciences, 2016
Aims: Cholera is an acute diarrheal disease that can lead to severe dehydration and death. Antibiotic resistance is a big challenge in infective disease like Cholera.
Afzali H.MD,, Momen-Heravi M.* MD,, Razzaghi R. MD   +2 more
doaj  

In Vitro Efficacy of Imipenem/Relebactam Against Imipenem Resistant Gram-Negative Strains Isolated from a Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objective: To determine in vitro efficacy of Imipenem/Relebactam against multi-drug resistant strains. Study Design: Cross-sectional study. Place and Duration of Study: Department of Microbiology, Fauji Foundation Hospital (FFH) Rawalpindi, Pakistan
Saima Ishtiaq, Sonia Tahir, Muhammad Waqas Abbas, Haider Ali, Saima Syed, Fatima Kareem   +5 more
doaj   +1 more source