Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Clinical complete response achieved in patients with breast cancer liver metastasis after personalized treatment: a case report and literature review. [PDF]
Front OncolWang Y, Jing N, Wang Y, Li N.
europepmc +1 more source
Advanced Functional Materials, EarlyView.The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner +4 more
wiley +1 more source
Whole-Genome Sequencing and Antimicrobial Resistance Analysis of Enterotoxigenic <i>Escherichia coli</i> F5 and F5-F41 Strains Isolated from Neonatal Calves in Inner Mongolia, China. [PDF]
Animals (Basel)Xie M +9 more
europepmc +1 more source
Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions
Advanced Functional Materials, EarlyView.This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian +7 more
wiley +1 more source
Overcoming cancer drug resistance through small-molecule targeting of HSP90 and HSP70. [PDF]
Cancer Drug ResistCai RD, Lin MJ, Ye QM.
europepmc +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Breaking biofilm barriers in skin wounds: Membrane-Active antimicrobials in an era of resistance. [PDF]
Curr Res Pharmacol Drug DiscovHemmingsen LM, Škalko-Basnet N.
europepmc +1 more source
Advanced Functional Materials, EarlyView.The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon +7 more
wiley +1 more source
Nanomedicine applications for the treatment of Staphylococcus aureus infections. [PDF]
FEMS Microbiol RevYedavally H, van Dijl JM, Salvati A.
europepmc +1 more source