Results 221 to 230 of about 2,071,500 (370)

Evolution of Antiviral Drug Resistance in SARS-CoV-2. [PDF]

Viruses
Dinata R, Baindara P, Mandal SM.
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

PYK2/FAK inhibitors reverse hypoxia-induced drug resistance in multiple myeloma

Haematologica, 2019
Barbara Muz, Maurizio Buggio, Feda Azab, Pilar de la Puente, Mark Fiala, Mahesh V. Padval, David T. Weaver, Jonathan A. Pachter, Ravi Vij, Abdel Kareem Azab   +9 more
doaj   +1 more source

Interactions within higher-order antibiotic combinations do not influence the rate of adaptation in bacteria. [PDF]

Evolution
Lozano-Huntelman NA, Cook E, Bullivant A, Ida N, Zhou A, Boyd S, Yeh PJ.   +6 more
europepmc   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning. [PDF]

Nat Commun
Saliba JG, Zheng W, Shu Q, Li L, Wu C, Xie Y, Lyon CJ, Qu J, Huang H, Ying B, Hu TY.   +10 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Mechanisms of resistance to NAMPT inhibitors in cancer. [PDF]

Cancer Drug Resist
Redler J, Nelson AE, Heske CM.
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

HIV multidrug class resistance prediction with a time sliding anchor approach. [PDF]

Bioinform Adv
Arslan N, Eggeling R, Reuter B, Van Leathem K, Pingarilho M, Gomes P, Sönnerborg A, Kaiser R, Zazzi M, Pfeifer N.   +9 more
europepmc   +1 more source