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ChemInform Abstract: Multiple Drug Resistance
ChemInform, 1999AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Delbert M. Shankel +3 more
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MULTIPLE DRUG–RESISTANT TUBERCULOSIS
Infectious Disease Clinics of North America, 1998The national and international emergence of drug-resistant M. tuberculosis has complicated both the programmatic control of the tuberculosis epidemic and the clinical management of individual cases. In the United States, the problem of MDR tuberculosis is regionalized and likely stems from multifactorial causes, including the concurrent HIV epidemic ...
Williamson Z. Bradford, Charles L. Daley
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Multiple drug resistance, antimutagenesis and anticarcinogenesis
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2005Many cells are protected from excess levels of exogenous chemicals, including mutagens and carcinogens as well as pharmaceutical agents, by being actively extruded through the action of one or more of a series of ATP-binding cassette drug transporter proteins. Those known to be important in humans are the multidrug resistance proteins (P-glycoproteins,
L. R. FERGUSON, DE FLORA, SILVIO
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Overcoming multiple drug resistance in cancer using polymeric micelles
Expert Opinion on Drug Delivery, 2018Introduction: A major concern that limits the success of cancer chemotherapy is multidrug resistance (MDR). The drug resistance mechanisms are either host related or tumor related.
S. S. Kesharwani +3 more
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Antibodies in the study of multiple drug resistance
Cytotechnology, 1993Multidrug resistance (MDR) is a major problem in cancer chemotherapy. As P-glycoprotein is the key molecule in MDR, many investigators have constructed anti-P-glycoprotein monoclonal antibodies (MAbs). Those antibodies, including MRK16 and C219, were used for elucidation of the mechanism of MDR and for overcoming of MDR.
Takashi Tsuruo, Yuji Heike
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Multiple drug resistance inAerobacter aerogenes [PDF]
Antonie van Leeuwenhoek, 1967 Multiple drug resistance resulting from continued growth in various drugs in turn followed by serial subculture in the simultaneous presence of all the drugs has been studied. In this way strains ofA. aerogenes resistant, in considerable measure, to 3, 4 and 5 drugs have been obtained.
P. J. Rodgers, P. G. Bolton, Dean Ac
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Directed Graphene-Based Nanoplatforms for Hyperthermia: Overcoming Multiple Drug Resistance.
Angewandte Chemie, 2018Multidrug resistance (MDR), which leads tumors resistance to traditional anticancer drugs, can cause the failure of chemotherapy treatments. Herein, we present a new way to overcome this problem using smart multifunctional graphene-based drug delivery ...
Zhaoxu Tu +6 more
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Multiple drug resistance and intermediate filaments
Cancer and Metastasis Review, 1996One major obstacle to the successful treatment of epithelial derived tumors, such as breast and prostate carcinoma, is the presence of a multiple drug resistance phenotype. The drug resistance which is observed in growing epithelial derived cancer cells could either be an intrinsic, selected and/or an acquired characteristic.
William S. Dalton, Anne E. Cress
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Multiple-Drug-Resistant Tuberculosis
Clinical Infectious Diseases, 1994The modern era of tuberculosis recently has been characterized by a rise in the number of cases of infection with multiple-drug-resistant (MDR) Mycobacterium tuberculosis. This acquisition of resistance to various established antituberculosis drugs has compromised both treatment and control programs worldwide.
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MULTIPLE PATHWAY DRUG-RESISTANCE (REVIEW)
International Journal of Oncology, 1993During the past few years it has become apparent that multiple mechanisms of resistance are playing a role in the clinical manifestations of drug resistance. In different organs and tumors, various components of the resistance phenotype are expressed to varying degrees.
M Volm, J Mattern
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