Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity [PDF]
, 2015 Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading.
Lockwood, Laura Anne Rebecca
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Metabolic Reprogramming in Thyroid Cancer [PDF]
Endocrinology and MetabolismThyroid cancer is a common endocrine malignancy with increasing incidence globally. Although most cases can be treated effectively, some cases are more aggressive and have a higher risk of mortality.
Sang-Hyeon Ju +5 more
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Advances in research on the relationship between thymoquinone and pancreatic cancer
Frontiers in Oncology, 2023 Pancreatic cancer has one of the worst prognoses among the most common cancers in the world. Its characteristics include a high rate of metastasis and chemotherapeutic resistance, which present major challenges to the medical community.
Zhanxue Zhao +5 more
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A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology [PDF]
, 2016 Pituitary adenomas are a common intracranial neoplasm, usually demonstrating a benign phenotype. They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and ...
Ansorge, Olaf +6 more
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Physiopathological Implications of 7TM Receptors [PDF]
, 2010 Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
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Characterization of cyclin E expression in multiple myeloma and its functional role in seliciclib-induced apoptotic cell death. [PDF]
PLoS ONE, 2012 Multiple Myeloma (MM) is a lymphatic neoplasm characterized by clonal proliferation of malignant plasma cell that eventually develops resistance to chemotherapy.
Liat Josefsberg Ben-Yehoshua +6 more
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Annexin A3, a Calcium-Dependent Phospholipid-Binding Protein: Implication in Cancer
Frontiers in Molecular Biosciences, 2021 Annexin A3 (ANXA3), also known as lipocortin III and placental anticoagulant protein III, has been reported to be dysregulated in tumor tissues and cancer cell lines, and harbors pronounced diagnostic and prognostic value for certain malignancies, such ...
Liu Yang +4 more
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Repurposing drugs to target nonalcoholic steatohepatitis [PDF]
, 2019 Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José +1 more
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Imatinib-induced interstitial pneumonitis – a literature review and case report [PDF]
, 2020 Imatinib is generally well tolerated, with mild common side effects such as nausea and vomiting, diarrhea, muscle cramps, fatigue, skin rash and edema; however, pulmonary complications are uncommon. A 73-year-old woman undergoing one month treatment with
Ciulei, George +12 more
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Cancer Biology & Medicine, 2012 Objective To explore the interaction of Anxa2 with P-Glycoprotein (P-gp) in the migration and invasion of the multidrug-resistant (MDR) human breast cancer cell line MCF-7/ADR.Methods A pair of short hairpin RNA (shRNA) targeting P-gp was transfected ...
Hai-chang Zhang +6 more
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