Results 11 to 20 of about 1,031,044 (237)
Microbiology Spectrum, 2023 With the application of bedaquiline (Bdq), the success rate of multidrug-resistant tuberculosis (MDR-TB) treatment has been significantly improved; however, the cardiac safety of the patients during treatment cannot be ignored. Hence, this study compared
Rong Li +6 more
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The Oncologist, 1996 Abstract Chemotherapy fails to cure most cancer patients with advanced disease, particularly patients with the most common forms of solid tumors. The presence or development of resistance to anticancer agents is the major cause of this failure.
Giaccone, G., Pinedo, H.M.
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malERA: An updated research agenda for insecticide and drug resistance in malaria elimination and eradication. [PDF]
PLoS Medicine, 2017 Resistance to first-line treatments for Plasmodium falciparum malaria and the insecticides used for Anopheles vector control are threatening malaria elimination efforts. Suboptimal responses to drugs and insecticides are both spreading geographically and
malERA Refresh Consultative Panel on Insecticide and Drug Resistance
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A Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections
Vaccines, 2023 Antibody Dependent Enhancement (ADE) of an infection has been of interest in the investigation of many viruses. It is associated with the severity of the infection.
Jyoti Sawant, Ajit Patil, Swarali Kurle
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Drugging Drug Resistance [PDF]
Cell, 2010 Resistance to anticancer drugs is widely observed in vitro and in cancer patients, but its prevalence is too high to be solely explained by the acquisition of mutations. Sharma et al. (2010) now report that dynamic chromatin modifications may be an independent route to drug resistance in cancer cells that can be reversed by epigenetic drugs.
Anton Berns, Jan-Hermen Dannenberg
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BMC Infectious Diseases, 2023 Background The World Health Organization has reported that the treatment success rate of multi-drug resistance tuberculosis is approximately 57% globally. Although new drugs such as bedaquiline and linezolid is likely improve the treatment outcome, there
J-B Ma +9 more
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Experimental Closed-Loop Control of Breast Cancer in Mice
Complexity, 2022 Cancer therapy optimization is an issue that can be solved using the control engineering approach. An optimal therapy generation algorithm is presented and tested using a tractable mouse model of breast cancer.
Levente Kovács +7 more
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mSystems, 2021 Accurate and timely functional genome annotation is essential for translating basic pathogen research into clinically impactful advances. Here, through literature curation and structure-function inference, we systematically update the functional genome ...
Samuel J. Modlin +10 more
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