Results 51 to 60 of about 1,255,487 (165)

PlyNJ3: a three-domain endolysin with broad-spectrum anti-streptococcal activity and synergistic efficacy against multidrug-resistant Streptococcus suis

BMC Veterinary Research
Background The global spread of multidrug-resistant (MDR) bacteria prompts the exploration of innovative antimicrobial strategies. Phage lysins—peptidoglycan hydrolases known for species-specific activity and low resistance potential—offer promising ...
Jiaqi Zhao, Jingju Wang, Peizhao Han, Cai Yin, Shushu Gu, Hui Ji, Xiaoming Wang, Liping Wang, Jinhu Huang   +8 more
doaj   +1 more source

Sudapyridine (WX-081) antibacterial activity against Mycobacterium avium, Mycobacterium abscessus, and Mycobacterium chelonae in vitro and in vivo

mSphere
Sudapyridine (WX-081) is a structural analog of bedaquiline (BDQ), which shows anti-tuberculosis and non-tuberculous mycobacteria (NTM) activities but, unlike BDQ, did not prolong QT interval in animal model studies.
Luyao Zheng, Hong Wang, Xueting Qi, Weiyan Zhang, Bin Wang, Lei Fu, Xi Chen, Xiaoyou Chen, Yu Lu   +8 more
doaj   +1 more source

Effective Mixed-Type Tissue Crusher and Simultaneous Isolation of RNA, DNA, and Protein from Solid Tissues Using a TRIzol-Based Method

J
One of the major challenges of studying biomarkers in tumor samples is the low quantity and quality of isolated RNA, DNA, and proteins. Additionally, the extraction methods ideally should obtain macromolecules from the same tumor biopsy, allowing better ...
Kelly Karoline dos Santos, Isabelle Watanabe Daniel, Letícia Carani Delabio, Manoella Abrão da Costa, Júlia de Paula Dutra, Bruna Estelita Ruginsk, Jeanine Marie Nardin, Louryana Padilha Campos, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Glaucio Valdameri, Vivian Rotuno Moure   +11 more
doaj   +1 more source

Murine Leukemia Viruses: Objects and Organisms

Advances in Virology, 2011
Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles.
Alan Rein
doaj   +1 more source

Predicting drug resistance

eLife
A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
Nicole S Arellano, Shannon E Elf
openaire   +3 more sources

Population genetic approaches to estimating the size of the HIV reservoir

Journal of Virus Eradication, 2015
J. Hattori, V. Boltz, W. Shao, M. Kearney, F. Maldarelli   +4 more
doaj   +1 more source

The alert for emergence of pig-associated MRSA ST 398 in multi-regions China

One Health
Livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA) lineage ST398 presents a notable public health risk through its transmission from pigs to humans.
Mingquan Cui, Hejia Wang, Ningning Han, Wenli Tang, Xiangbin Song   +4 more
doaj   +1 more source

Hybrid sequencing of chromosome and plasmids from multidrug-resistant Escherichia coli isolated in Cambodia: Are megaplasmids vectors of antibiotic resistance genes?

Journal of Global Antimicrobial Resistance
Objectives: The prevalence of antimicrobial resistance (AMR) in Escherichia coli infections in Cambodia is high and increasing, yet data distinguishing plasmid- and chromosome-mediated AMR spread remain limited.
Ella Marcy, Sivhour Chiek, Mallorie Hidé, Savatey Hak, Chiva Ma, Meymey Lem, Gauthier Delvallez, Anne-Laure Bañuls, Sokleaph Cheng, Juliette Hayer   +9 more
doaj   +1 more source

Resisting drugs [PDF]

Nature Reviews Genetics, 2000
openaire   +2 more sources

Antiviral drug resistance [PDF]

BMJ, 1996
D, Pillay, A M, Geddes
openaire   +2 more sources