Drug resistant epilepsy - Open Access .click

Results 201 to 210 of about 2,749,589 (298)

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Epilepsia, EarlyView.
Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes.
Mohammed A. AlQahtani +7 more
wiley +1 more source

Moving beyond spike detection: High frequency‐driven masking improves seizure onset zone localization in intracranial electroencephalography

Epilepsia, EarlyView.
Abstract Objective Interictal epileptiform spikes (IESs) are widely used biomarkers of epileptogenic tissue in presurgical epilepsy evaluation. However, their reliability for seizure onset zone (SOZ) localization in high‐density intracranial electroencephalography (iEEG) remains inconsistent.
Amir Hossein Ayyoubi +16 more
wiley +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

Epilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo +91 more
wiley +1 more source

Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Addison C. Cavender +15 more
wiley +1 more source

Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review. [PDF]

PLoS One
Vaccarezza MM, Sanguine VL, Balaciano G.
europepmc +1 more source

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia +19 more
wiley +1 more source

Case Report: Seizure freedom after resection of a temporal choroidal fissure cyst in drug-resistant epilepsy. [PDF]

Front Neurosci
Fu G, Ye F, Lu S, Sun X, Zhou P.
europepmc +1 more source

Epilepsia, EarlyView.
Abstract Objective Climate‐related exposures, including air pollution, temperature extremes, humidity, and atmospheric conditions, are increasingly recognized as potential seizure triggers. As climate change intensifies, understanding the environmental contributors to pediatric seizure risk has important implications for anticipatory guidance and ...
Caroline Sarpy +5 more
wiley +1 more source

drug-resistant epilepsy
epilepsy
drug resistance

epilepsy surgery
neuropsychiatry
seizures

neuroinflammation
children
neurosciences