Results 221 to 230 of about 2,749,589 (298)

Surgical Management in Patients With Drug-Resistant Epilepsy: A Summary of Four Systematic Reviews and Meta-Analyses. [PDF]

Epilepsy Curr
Roldan Y, Jobst BC, Garcia-Aquino D, Ghandour D, Nasif MB, Duda T, Eid A, Hart S, Kesserwan M, Martyniuk A, Lannon M, Saber G, Saouda C, Sharma S, Vinarsky V, Strickland SL, Busch RM, Hopp JL, Gonzalez-Martinez J, Bergey G, Darzi AJ.   +20 more
europepmc   +1 more source

How much does the reduced electroencephalographic montage matter for seizure detection? A large‐cohort simulation study

Epilepsia, EarlyView.
Abstract Objective Subscalp electroencephalographic (EEG) systems with few channels have emerged as promising solutions for ultra‐long‐term seizure monitoring, but the impact of montage configuration on automated seizure detection is unclear. We compared automated detection performance between full‐scalp and simulated reduced montages approximating ...
Joe Kojima, Haoer Shi, Svanik Jaikumar, William K. S. Ojemann, Carlos Aguila, Juri Kim, Taneeta Mindy Ganguly, Brian Litt, Erin C. Conrad   +8 more
wiley   +1 more source

Non-invasive preoperative prediction of surgical outcomes in drug-resistant epilepsy using seizure-related EEG network dynamics. [PDF]

Front Neurosci
Feng R, Luo Q, Yang D, Kong W, Han Y, Lin W, Shi Z, Li Q.   +7 more
europepmc   +1 more source

Characterizing sleep disturbances in developmental and epileptic encephalopathies through natural language processing: A retrospective monocentric study

Epilepsia, EarlyView.
Abstract Objective Sleep disorders are frequent but undercharacterized comorbidities in developmental and epileptic encephalopathies (DEEs). We aimed to estimate the frequency, spectrum, and burden of sleep disturbances across genetic DEE subtypes using real‐world data extracted from electronic health records (EHRs) through natural language processing (
Tommaso Lo Barco, Maxime Douillet, Nicole Chemaly, Audrey Duval, Gianluca D'onofrio, Nicolas Garcelon, Xiaoyi Chen, Rima Nabbout   +7 more
wiley   +1 more source

Ketogenic diet fails to mitigate seizures and neuroinflammatory responses in a mouse model of virus‐induced epilepsy

Epilepsia, EarlyView.
Abstract Objective The ketogenic diet (KD) is a high‐fat, low‐carbohydrate intervention widely used to treat drug‐resistant epilepsy, thought to reduce seizures through a combination of metabolic, neuronal, and microbiota‐dependent mechanisms. Additionally, recent studies suggest that the anticonvulsant effects of KD require the gut microbiota, with ...
Casey H. Meili, Kaitlyn Allen, Daniel J. Doty, Sofia Del Fiol, Ana Beatriz DePaula‐Silva   +4 more
wiley   +1 more source

A first in disease trial of the safety, tolerability, and anti-seizure effects of ES-481 in drug-resistant epilepsy. [PDF]

Epilepsia Open
Foster EC, Millist L, Germaine J, Chamorro S, Roberts C, Nicolo JP, Hosking S, Perucca P, Mullen S, Robinson H, Wharrie R, Walsh B, Reutens D, Irwin K, Zeng H, Niecestro R, O'Brien TJ.   +16 more
europepmc   +1 more source

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

Epilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez, Mustafa Q. Hameed, Yongho Choe, Gabrielle E. McGinty, Amanda M. Liebhardt, Rui Lin, Benjamin Hui, Yini Liang, David J. Arce, Henry H. C. Lee, Mustafa Sahin, Alexander Rotenberg   +11 more
wiley   +1 more source

Multimodal neuroimaging fusion in presurgical evaluation of drug-resistant epilepsy: current evidence, clinical integration, and future directions. [PDF]

Front Neurosci
Zhao Y, Wang M, Shen B, Luo W.
europepmc   +1 more source