Results 31 to 40 of about 39,256 (202)

The Concept of Drug-Resistant Epileptogenic Zone

open access: yesFrontiers in Neurology, 2019
Resective surgery is the most effective way to treat drug-resistant epilepsy. Despite extensive pre-surgical evaluation, only 30–70% patients would become seizure-free after surgery.
Chunbo Zhang, Patrick Kwan, Patrick Kwan
doaj   +1 more source

Surgical Management for drug-resistant Epilepsy in Medial Temporal Lobe Lesions (Al-Azhar experience) [PDF]

open access: yesAl-Azhar International Medical Journal, 2022
Background: The most common cause of drug resistant epilepsy is the temporal lobe seizures especially that caused by medial temporal lobe epileptogenic lesions.
alaa ibrahim, mohamed rashad
doaj   +1 more source

Health technology assessment report on the presurgical evaluation and surgical treatment of drug-resistant epilepsy

open access: yes, 2013
PURPOSE: Epilepsy is a neurologic disorder with major social impact. Surgery is a valuable option in patients who are not responding to antiepileptic drugs.
C. o. Epilepsy   +13 more
core   +2 more sources

Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]

open access: yes, 2014
Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
core   +1 more source

Revisiting the concept of drug-resistant epilepsy: A TASK1 report of the ILAE/AES Joint Translational Task Force [PDF]

open access: yes, 2023
Despite progress in the development of anti-seizure medications (ASMs), one third of people with epilepsy have drug-resistant epilepsy (DRE). The working definition of DRE, proposed by the International League Against Epilepsy (ILAE) in 2010, helped ...
Galanopoulou, Aristea S   +6 more
core  

Epilepsy and drug-resistant epilepsy in children with cerebral palsy: A retrospective observational study [PDF]

open access: yes, 2020
Purpose: The objective of this study was to determine risk factors for epilepsy and drug-resistant epilepsy (DRE) development in children with cerebral palsy.
Dilek, Mustafa   +3 more
core   +1 more source

Drug Resistant Epilepsy Among Patients Attended The Neurosciences Hospital

open access: yesمجله كليه طب الكندي, 2019
Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom. Up to 30% of patients referred to clinics with a diagnosis of
Nael Husain Zaer
doaj   +1 more source

Surgery in Epilepsy – How Advances in Human Neurology Can Benefit Veterinary Patients

open access: yesVeterinary Evidence, 2016
This article reports the evidence behind pre-surgical evaluation and epilepsy surgery in human patients with drug-resistant idiopathic epilepsy and how this could potentially form the basis for the treatment of canine drug-resistant epilepsy in the ...
Marios Charalambous
doaj   +1 more source

MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy

open access: yesFrontiers in Pharmacology, 2021
One-third of patients with epilepsy suffer from drug-resistant epilepsy (DRE). Valproic acid (VPA) is a classic anticonvulsant drug, and its resistance is a crucial predictor of DRE, but the pathogenesis remain unknown.
Meng Fu   +7 more
doaj   +1 more source

Stress regulation in drug-resistant epilepsy [PDF]

open access: yesEpilepsy & Behavior, 2017
The prevalence of psychological distress, especially depressive and anxiety disorders, is higher in epilepsy than in other chronic health conditions. These comorbid conditions contribute even more than epileptic seizures themselves to impaired quality of life in patients with epilepsy (PWE).
Kotwas, Iliana   +4 more
openaire   +4 more sources

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