Results 11 to 20 of about 366,264 (296)
Clinical, radiological and electrophysiological predictors for drug-resistant epilepsy
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Background Epilepsy is the third chronic brain illness worldwide. About a third of the epileptic patients will be drug resistant. Early identification of these patients is critical for appropriate treatment selection and prevention of the devastating ...
Noha T. Abokrysha +5 more
doaj +2 more sources
Ketogenic diets for drug-resistant epilepsy. [PDF]
Cochrane Database of Systematic Reviews, 2020 BACKGROUND Ketogenic diets (KDs) are high in fat and low in carbohydrates and have been suggested to reduce seizure frequency in people with epilepsy. Such diets may be beneficial for children with drug-resistant epilepsy.
K. Martin-McGill +3 more
semanticscholar +5 more sources
Epilepsia Open, 2022 More than one‐third of people with epilepsy develop drug‐resistant epilepsy (DRE). Different hypotheses have been proposed to explain the origin of DRE. Accumulating evidence suggests the contribution of neuroinflammation, modifications in the integrity ...
Patricia Campos‐Bedolla +2 more
doaj +2 more sources
Drug-Resistant Epilepsy and Surgery [PDF]
Current Neuropharmacology, 2017 Epilepsy is a chronic brain disease that is caused by various factors and characterized by recurrent, episodic and temporary central nervous system dysfunction which results due to excessive discharge of brain neurons. In the past decades, despite the continuous development of antiepileptic drugs, there are still many patients with epilepsy progressing
Sheng, Jiyao +4 more
openaire +4 more sources
Clinical Management of Drug Resistant Epilepsy: A Review on Current Strategies
Neuropsychiatric Disease and Treatment, 2021 Drug resistant epilepsy (DRE) is defined as the persistence of seizures despite at least two syndrome-adapted antiseizure drugs (ASD) used at efficacious daily dose.
D. Guery, S. Rheims
semanticscholar +3 more sources
Surgery for drug-resistant focal epilepsy
Annals of Indian Academy of Neurology, 2014 During the colloquium on drug-resistant epilepsy (DRE) at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore on August 16-18, 2013, a number of presentations were made on the surgically remediable lesional epilepsy syndromes ...
Malla Bhaskara Rao +6 more
doaj +3 more sources
The epidemiology of drug‐resistant epilepsy: A systematic review and meta‐analysis
Epilepsia, 2018 The definition of drug‐resistant epilepsy (DRE) affects case identification and treatment, and impacts prevalence or incidence estimates and health burden estimation in epidemiology.
L. Kalilani +4 more
semanticscholar +3 more sources
Pathogenesis of drug resistant epilepsy
Эпилепсия и пароксизмальные состояния, 2019 Pharmacotherapy is the first-line treatment modality for epilepsy. However, in 20-40% of patients, epilepsy is resistant to pharmacotherapy. These numbers have not changed for decades despite the development and use of antiepileptic drugs with novel ...
S. M. Malyshev +3 more
doaj +3 more sources
Neuromodulation in Drug Resistant Epilepsy [PDF]
Aging and disease, 2021 Epilepsy affects approximately 70 million people worldwide, and it is a significant contributor to the global burden of neurological disorders. Despite the advent of new AEDs, drug resistant-epilepsy continues to affect 30-40% of PWE. Once identified as having drug-resistant epilepsy, these patients should be referred to a comprehensive epilepsy center
Rincon, Natalia +2 more
openaire +2 more sources
Science Translational Medicine, 2023 Precise estimates of epileptogenic zone networks (EZNs) are crucial for planning intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual epileptic patient (VEP), a workflow that uses personalized brain models and ...
Huifang E. Wang +13 more
semanticscholar +1 more source