Results 61 to 70 of about 39,256 (202)

Psychiatric symptoms and comorbidities in patients with drug-resistant epilepsy in presurgical assessment—A prospective explorative single center study

open access: yesFrontiers in Psychiatry, 2022
IntroductionPeople with epilepsy (PWE) have a higher prevalence of psychiatric disorders. Some individuals with drug-resistant epilepsy might benefit from surgical interventions.
Fabian Friedrich   +6 more
doaj   +1 more source

Clinical predictors of drug-resistant epilepsy in children

open access: yes, 2021
Background/aim: In up to 20% of epilepsy patients, seizures may not be controlled despite the use of antiepileptic drugs, either alone or in combination. These individuals are considered to have drug-resistant epilepsy. Drug-resistant epilepsy is usually
YİŞ, ULUÇ   +4 more
core   +1 more source

Association between Genetic Polymorphism of SCN1A, GABRA1 and ABCB1 and Drug Responsiveness in Vietnamese Epileptic Children

open access: yesMedicina
Background and Objectives: Drug resistant epilepsy (DRE) is a major hurdle in epilepsy, which hinders clinical care, patients’ management and treatment outcomes.
Hai Xuan Tang   +7 more
doaj   +1 more source

Coexistence of idiopathic generalized epilepsy among surgically treated patients with drug-resistant temporal lobe epilepsy

open access: yes, 2011
Introduction: Failure to identify the association antiepileptic drug (AED)-resistant temporal lobe epilepsy (TLE) with idiopathic generalized epilepsy (IGE) can interfere with decision for anterior temporal lobectomy (ATL) and prediction of post-ATL ...

core   +1 more source

Drug‐resistant epilepsy and mortality—Why and when do neuromodulation and epilepsy surgery reduce overall mortality

open access: yes, 2022
International audienceAbstract Patients with drug‐resistant epilepsy have an increased mortality rate, with the majority of deaths being epilepsy related and 40% due to sudden unexpected death in epilepsy (SUDEP).
Mickael R. Sperling   +8 more
core   +1 more source

Current Principles in the Management of Drug-Resistant Epilepsy [PDF]

open access: yes, 2022
Drug-resistant epilepsy is associated with poor health outcomes and increased economic burden. In the last three decades, various new antiseizure medications have been developed, but the proportion of people with drug-resistant epilepsy remains ...
Shlobin, Nathan, Sander, Josemir
core  

A study of drug-resistant childhood epilepsy testing the new ILAE criteria

open access: yes, 2012
PurposeTo test the new ILAE definition of drug-resistant epilepsy in a cohort study.MethodsAll children younger than 14 with two or more unprovoked seizures observed at our hospital between 1994 and 2008 were included.ResultsFive hundred and eight ...
Aguilera-López, Patricia   +4 more
core   +1 more source

Alterations of apparent diffusion coefficient from ultra high b‐values in the bilateral thalamus and striatum in MRI‐negative drug‐resistant epilepsy

open access: yesEpilepsia Open
Objective Subcortical nuclei such as the thalamus and striatum have been shown to be related to seizure modulation and termination, especially in drug‐resistant epilepsy.
Guixian Tang   +13 more
doaj   +1 more source

Deep brain stimulation in drug-resistant epilepsy: current status and future perspectives

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Drug-resistant epilepsy remains a major challenge in management of epilepsy, with approximately half of patients being unsuitable candidates for resective surgery.
HU Tian-qi, XIE Hu-tao, ZHANG Jian-guo
doaj   +1 more source

Antiepileptic Drug Therapy in Patients with Drug-Resistant Epilepsy [PDF]

open access: yesJournal of Epilepsy Research, 2019
Antiepileptic drug (AED) therapy starts with an accurate diagnosis of epilepsy and is followed by sequential drug trials. Seizure freedom is largely achieved by the first two drug trials; thus, epilepsy that cannot be controlled after appropriately conducted trials of the first two drugs is defined as drug-resistant epilepsy (DRE).
Park, Kang Min   +2 more
openaire   +2 more sources

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