A case report: retigabine induced oral mucosal dyspigmentation of the hard palate [PDF]
Background Dyspigmentation of the oral mucosa has a multitude of aetiological causes. Retigabine, a new antiepileptic drug, has the potential side effect of inducing a blue/purple pigmentation of the oral mucosa in addition to the skin, lips, nails and ...
Beacher, Nicholas G. +2 more
core +1 more source
Stress regulation in drug-resistant epilepsy [PDF]
The prevalence of psychological distress, especially depressive and anxiety disorders, is higher in epilepsy than in other chronic health conditions. These comorbid conditions contribute even more than epileptic seizures themselves to impaired quality of life in patients with epilepsy (PWE).
Kotwas, Iliana +4 more
openaire +2 more sources
Effect of neurostimulation on cognition and mood in refractory epilepsy. [PDF]
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to ...
Chan, Alvin Y +3 more
core +1 more source
One-third of patients with epilepsy suffer from drug-resistant epilepsy (DRE). Valproic acid (VPA) is a classic anticonvulsant drug, and its resistance is a crucial predictor of DRE, but the pathogenesis remain unknown.
Meng Fu +7 more
doaj +1 more source
Mindfulness-based interventions in epilepsy: a systematic review [PDF]
Mindfulness based interventions (MBIs) are increasingly used to help patients cope with physical and mental long-term conditions (LTCs). Epilepsy is associated with a range of mental and physical comorbidities that have a detrimental effect on quality of
AM Kanner +45 more
core +3 more sources
Surgery in Epilepsy – How Advances in Human Neurology Can Benefit Veterinary Patients
This article reports the evidence behind pre-surgical evaluation and epilepsy surgery in human patients with drug-resistant idiopathic epilepsy and how this could potentially form the basis for the treatment of canine drug-resistant epilepsy in the ...
Marios Charalambous
doaj +1 more source
Validated outcome of treatment changes according to International League Against Epilepsy criteria in adults with drug-resistant focal epilepsy. [PDF]
OBJECTIVE: Although many studies have attempted to describe treatment outcomes in patients with drug-resistant epilepsy, results are often limited by the adoption of nonhomogeneous criteria and different definitions of seizure freedom.
Alexandre V +20 more
core +2 more sources
The Role of Neuroinflammation and Network Anomalies in Drug-Resistant Epilepsy
Epilepsy affects over 50 million people worldwide. Drug-resistant epilepsy (DRE) accounts for up to a third of these cases, and neuro-inflammation is thought to play a role in such cases.
Jianwei Shi +6 more
semanticscholar +1 more source
EXPLORING COGNITIVE IMPAIRMENTS IN DRUG-RESISTANT EPILEPSY: INSIGHTS FROM A COMPARATIVE ANALYSIS
This article explores the cognitive impairments in individuals with drug-resistant epilepsy compared to those with well-controlled epilepsy. The research involves 102 subjects (62 with drug-resistant epilepsy and 40 with well-controlled epilepsy), and ...
DOTEN, Natalia
doaj +1 more source
Lennox-Gastaut Syndrome: A State of the Art Review. [PDF]
Lennox-Gastaut syndrome (LGS) is a severe age-dependent epileptic encephalopathy usually with onset between 1 and 8 years of age. Functional neuroimaging studies recently introduced the concept of Lennox-Gastaut as "secondary network epilepsy" resulting ...
Mastrangelo, Mario
core +1 more source

