Results 81 to 90 of about 366,264 (296)
Currently no sensitive and specific biomarkers exist to predict drug‐resistant epilepsy. We determined whether blood levels of high‐mobility group box 1 (HMGB1), a mediator of neuroinflammation implicated in drug‐resistant epilepsies, identifies patients
L. Walker +8 more
semanticscholar +1 more source
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Clinical diagnostic features and surgical outcomes of mesial temporal lobe epilepsy
Despite certain successes in the treatment of epilepsy, primarily associated with the active development of pharmacology, in 30% of cases, there is a resistant course, especially focal forms of temporal lobe epilepsy.
O. P. Subbotina +2 more
doaj +1 more source
Definitions of Drug-Resistant Epilepsy for Administrative Claims Data Research
Background and Objective To assess the accuracy of definitions of drug-resistant epilepsy applied to administrative claims data. Methods We randomly sampled 450 patients from a tertiary health system with ≥1 epilepsy/convulsion encounter, ≥2 distinct ...
C. Hill +6 more
semanticscholar +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
EVALUATION OF THE PSYCHOLOGICAL INTERVENTION PROGRAM APPLIED TO PEOPLE WITH DRUG-RESISTANT EPILEPSY [PDF]
Drug-resistant epilepsy presents a myriad of psychological challenges, including cognitive decline, emotional and behavioral disturbances, loss of autonomy, stigma, psychosocial dysfunction, and a heightened risk of trauma and premature death, all of ...
DOȚEN Natalia
doaj +1 more source
Efficacy of modified atkins ketogenic diet in chronic cluster headache. An open-label, single-arm, clinical trial [PDF]
Introduction: Drug-resistant cluster headache (CH) is still an open clinical challenge. Recently, our group observed the clinical efficacy of a ketogenic diet (KD), usually adopted to treat drug-resistant epilepsies, on migraine.
Cherubino Di Lorenzo +9 more
core +3 more sources
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy
Responsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures.
Nilika S. Singhal +6 more
doaj +1 more source
Epilepsy is a common neurological disorder affecting 0.6–0.75% of dogs in veterinary practice. Treatment is frequently complicated by the occurrence of drug-resistant epilepsy and cluster seizures in dogs with idiopathic epilepsy.
Sandra R. P. Kriechbaumer +12 more
doaj +1 more source

