Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese
, 2007 There is accumulating evidence to suggest that overexpression of efflux drug transporters at the blood-brain barrier, by reducing antiepileptic drug (AED) accumulation in the seizure foci, contributes to drug resistance in epilepsy.
Hui, ACF +8 more
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Localizing Seizure-Onset Zones in Presurgical Evaluation of Drug-Resistant Epilepsy by Electroencephalography/fMRI: Effectiveness of Alternative Thresholding Strategies [PDF]
, 2012 Simultaneous EEG/fMRI is an effective noninvasive tool for identifying and localizing the SOZ in patients with focal epilepsy. In this study, we evaluated different thresholding strategies in EEG/fMRI for the assessment of hemodynamic responses to IEDs ...
Scheidegger, O +8 more
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Role of vagus nerve stimulation in epilepsy
Quality in SportIntroduction and purpose: Epilepsy affects 1% globally, with 2.6 to 6 million cases in Europe. 30-40% of the 50 million epilepsy patients globally don't respond to drugs.
Bożena Kmak
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Epilepsy Surgery in Pediatric Patients: A Single-Center Experience
, 2019 Objectives:Epilepsy surgery is one of the treatment options in pediatric patients with drug-resistant epilepsy. Our aim is to share demographic data, surgical outcome, possible surgical complications, and factors that affect surgical outcome in pediatric
Bahattin TANRIKULU +2 more
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Drug-resistant epilepsy treated with a vagus nerve stimulator – case report and literature review
Journal of Education, Health and SportThe average incidence of epilepsy worldwide is estimated at 7.60 cases per 1,000 inhabitants, with an average annual incidence of 67.77 cases per 100,000 inhabitants. Epilepsy is one of the most common neurological diseases. However, it is not a disease
Michał Leśniewski +7 more
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Defining drug-resistant epilepsy
, 2011 Drug resistant epilepsy remains a major clinical challenge. Diverse criteria have been used to defi ne drug resistance by different researchers, making it diffi cult or even impossible to compare the results across different studies.
Patrick Kwan
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, 2009 This is a prospective study of a consecutive series of children undergoing epilepsy surgery. The main aims were to evaluate the heterogeneity with respect to psychopathology and IQ, and to use a global assessment scale (Children's Global Assessment Scale
Danielsson, Susanna, +5 more
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Serum α-Synuclein in Pediatric Refractory Epilepsy: Correlation with Diagnosis and Clinical Severity
MedicinaBackground and Objectives: Epilepsy is a common neurological disrupt that involves recurring seizures. α-Synuclein (α-Syn), one of the most abundant proteins in the nervous system, is implicated in both neurodegenerative conditions and epilepsy.
Aida M. S. Salem +7 more
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Drug-resistant epilepsy associated with cortical dysplasias
, 2013 Epilepsy associated with malformations of the cerebral cortex is reported in the literature to account for up to 25% of the total cases of symptomatic epilepsies. It is characterized by the most severe course and often induces drug-resistance in seizures.
I. E. Poverennova, T. V. Kuznetsova
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Beyond the seizures: Ketogenic Diets in the battle against drug-resistant epilepsy
Journal of Education, Health and SportIntroduction: Epilepsy is a chronic, non-infectious and one of the most common neurological disease. About 70 million people worldwide suffer from it and these are patients of all ages. Despite the existence of many anticonvulsants and multiple lines of
Natalia Domańska +5 more
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