Results 71 to 80 of about 2,749,589 (298)

Epilepsy and drug-resistant epilepsy in neurocutaneous syndromes

Northwestern Medical Journal, 2023
Aim: Epilepsy frequently accompanies neurocutaneous syndromes. Due to the comorbid conditions that epileptic seizures may cause, their frequency, type, and duration also affect the prognosis of neurocutaneous diseases. The purpose of this study was to examine the frequency of epilepsy and drug-resistant epilepsy in neurocutaneous syndromes, and factors
Ayşegül Danış, Fatma Hancı
openaire   +2 more sources

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Current approaches to neurosurgical treatment for drug-resistant focal epilepsy in adults

Неврология, нейропсихиатрия, психосоматика, 2018
The review is dedicated to the problems of current neurosurgical treatment for drug-resistant epilepsy in the adult population of Russia and foreign countries. The literature published in the period  2010–2017 was sought in Russian and foreign databases.
E. A. Narodova, A. A. Narodov, N. A. Shnayder, D. V. Dmitrenko, I. G. Strotskaya   +4 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Early epilepsy surgery for non drug-resistant patients

Epilepsy & Behavior Reports, 2022
The aim of epilepsy treatment is to achieve seizure freedom. Surgery is often still considered a late option when pharmacological treatments have failed and epilepsy has become drug-resistant.We analyse the clinical features and surgical outcome in ...
Veronica Pelliccia, Francesco Deleo, Francesca Gozzo, Ginevra Giovannelli, Roberto Mai, Massimo Cossu, Laura Tassi   +6 more
doaj   +1 more source

Association between Genetic Polymorphism of SCN1A, GABRA1 and ABCB1 and Drug Responsiveness in Vietnamese Epileptic Children

Medicina
Background and Objectives: Drug resistant epilepsy (DRE) is a major hurdle in epilepsy, which hinders clinical care, patients’ management and treatment outcomes.
Hai Xuan Tang, Muoi Dang Ho, Nhung Phuong Vu, Hung Vu Cao, Vinh Anh Ngo, Van Thi Nguyen, Thuan Duc Nguyen, Ton Dang Nguyen   +7 more
doaj   +1 more source

Psychiatric symptoms and comorbidities in patients with drug-resistant epilepsy in presurgical assessment—A prospective explorative single center study

Frontiers in Psychiatry, 2022
IntroductionPeople with epilepsy (PWE) have a higher prevalence of psychiatric disorders. Some individuals with drug-resistant epilepsy might benefit from surgical interventions.
Fabian Friedrich, Ekaterina Pataraia, Susanne Aull-Watschinger, Sonja Zehetmayer, Lisbeth Weitensfelder, Clara Watschinger, Nilufar Mossaheb   +6 more
doaj   +1 more source

Localizing Seizure-Onset Zones in Presurgical Evaluation of Drug-Resistant Epilepsy by Electroencephalography/fMRI: Effectiveness of Alternative Thresholding Strategies [PDF]

, 2012
Simultaneous EEG/fMRI is an effective noninvasive tool for identifying and localizing the SOZ in patients with focal epilepsy. In this study, we evaluated different thresholding strategies in EEG/fMRI for the assessment of hemodynamic responses to IEDs ...
Scheidegger, O, Jann, K, Schindler, K, Koenig, T, Meyer, K, Rummel, C, Hauf, M, Mariani, L, Wiest, R, Jann, Kay, Scheidegger, Olivier, Hauf, Martinus, Rummel C, Meyer K, Schindler, Kaspar, Jann K, Scheidegger O, Schindler K, Wiest R, Mariani L, Wiest, Roland Gerhard Rudi, Koenig T, König, Thomas, Hauf M   +23 more
core   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

Complementing Engel Classification: Postoperative Scalp EEG as an Objective Indicator in SEEG‐Guided Radiofrequency Thermocoagulation—A Seizure‐Onset Pattern‐Based Stratified Analysis—

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang, Rui Zhang, Haiyan Ma, Lu Yang, Xuefeng Qu, Qiqi Chen, Yan Zhang   +6 more
wiley   +1 more source