Results 251 to 260 of about 8,989,140 (356)

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.

Cell Stem Cell, 2016
Elena Matsa, P. Burridge, Kun-Hsing Yu, John H Ahrens, Vittavat Termglinchan, Haodi Wu, Chun Liu, Praveen K. Shukla, N. Sayed, Jared M. Churko, Ningyi Shao, Nicole A Woo, Alexander S Chao, Joseph D. Gold, I. Karakikes, M. Snyder, Joseph C. Wu   +16 more
semanticscholar   +1 more source

Adaptive Hydrogels With Spatiotemporal Stiffening Using pH‐Modulating Enzymes

Advanced Functional Materials, EarlyView.
The chemomechanical coupling in an adaptive hydrogel is studied to further the development of adaptive hydrogels. This coupling is achieved by embedding a pH‐modulating enzyme in a pH‐responsive hydrogel. The enzymatic reaction can be triggered locally, which generates a pH‐decreasing wave throughout the system, increasing the crosslinking density and ...
Natascha Gray, Zoe Grämiger, André R. Studart, Rafael Libanori   +3 more
wiley   +1 more source

Rethinking drug safety signal detection and causality assessment in the age of AI: the risks of incomplete data and biased insights. [PDF]

Front Drug Saf Regul
Chhikara P, Hammad TA.
europepmc   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

[Drug safety: advances and challenges on the path to excellence at Brazilian hospitals]. [PDF]

Cad Saude Publica
Pessoa GR, Silva LMSD, Trigueiro JG, Silva TCD.   +3 more
europepmc   +1 more source

Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films

Advanced Functional Materials, EarlyView.
Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee, Yun‐Tae Kim, Hwarang Choi, Sanghwan Park, Seongyeop Lim, Chang Young Lee   +5 more
wiley   +1 more source

A genomic-led strategy to anticipate drug safety effects

Ferolito BR, Horimoto AR, Gravel-Pucillo K, Golden DJ, Dashti H, Giambartolomei C, Rasooly D, Matty R, Gaziano L, Tsepilov Y, Costa L, Kosik N, Ioannidis H, Karim M, Winicki G, Hunter F, Langenberg C, Whittaker JC, Million Veteran Program, Cai T, Peloso GM, Zdrazil B, Ghoussaini M, Leach AR, Muralidhar S, Smit IA, Casas JP, Gaziano JM, Cho K, Pereira AC.   +29 more
europepmc   +1 more source

Pharmacovigilance: the evolution of drug safety monitoring. [PDF]

J Pharm Policy Pract
Khan MAA, Sara T, Babar ZU.
europepmc   +1 more source

Single‐ and Dual‐Atom Configurations in Atomically Dispersed Catalysts for Lithium–Sulfur Batteries

Advanced Functional Materials, EarlyView.
Single‐atom and dual‐atom‐based atomically dispersed catalysts (ADCs) effectively address the shuttle effect and sluggish redox kinetics in Li–S batteries. With nearly 100% atomic utilization and tunable coordination environments, ADCs enhance LiPSs adsorption, lower conversion barriers, and accelerate sulfur redox reactions.
Haoyang Xu, Zhenfeng Li, Yue Fei, Ali Mohammadi, Ge Li   +4 more
wiley   +1 more source

Outpatient interface challenges for drug safety in Parkinson's disease patients: a questionnaire based cross-sectional study. [PDF]

Front Neurol
Greten S, Niesmann C, Krey L, Heck J, Wegner F, Klietz M.   +5 more
europepmc   +1 more source