Results 231 to 240 of about 8,989,140 (356)

The Opportunities of Metabolomics in Drug Safety Evaluation

Current Pharmacology Reports, 2017
Pengcheng Wang, Amina I. Shehu, Xiaochao Ma   +2 more
semanticscholar   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals. [PDF]

Clin Pharmacol Ther
Tan GSQ, Miller L, Wade S, Ilomäki J, Lukose D, Rong J, Webb GI.   +6 more
europepmc   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Class-level drug safety surveillance in hospital practice: A pharmacovigilance analysis of 84 therapeutic subclasses from a South Asian tertiary care center. [PDF]

Explor Res Clin Soc Pharm
Umer A, Mohmand AK, Khan NM, Arshad A, Sethi SM.   +4 more
europepmc   +1 more source

Dual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy

Advanced Functional Materials, EarlyView.
A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren   +6 more
wiley   +1 more source

Performance of the Self-Controlled Case Series With Active Comparators for Drug Safety Signal Detection Using the Clinical Practice Research Datalink (CPRD). [PDF]

Pharmacoepidemiol Drug Saf
Coste A, Wong AYS, Haguinet F, Bate A, Douglas IJ.   +4 more
europepmc   +1 more source

Drug safety on trial [PDF]

Nature, 2005
openaire   +2 more sources

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

Experimental biology and medicine, 2016
L. Vernetti, N. Senutovitch, R. Boltz, R. Debiasio, Tong Ying, Shun, A. Gough, D. L. Taylor   +7 more
semanticscholar   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source