Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang +4 more
wiley +1 more source
Performance of active drug safety monitoring and management for pharmacovigilance strengthening in Ethiopia, experience from a multidrug-resistant tuberculosis management program: a cross-sectional study. [PDF]
Achalu DL +8 more
europepmc +1 more source
Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen +7 more
wiley +1 more source
Research progress on the intrinsic link between the occurrence and progression of malignant tumors, chronic kidney disease and drug safety. [PDF]
Zhang D, Jiang S, Liu L, Lu J, Li W.
europepmc +1 more source
Descriptor‐Informed Screening of Interface‐Active Molecules for Efficient Magnesium Metal Anodes
A descriptor‐informed molecular screening strategy identifies 4‐bromo‐N, N‐dimethylaniline (BrNNA) as an interface‐active electrolyte component that enables fast Mg stripping/plating in Mg(TFSI)2‐based electrolytes. By simultaneously regulating Mg2+ solvation and interphase formation, the BrNNA‐containing electrolyte delivers activation‐free Mg ...
Hao Xu +16 more
wiley +1 more source
Real-world assessment of sparsentan's drug safety framework. [PDF]
Fu W, Wang J, Xue Y, Pan D.
europepmc +1 more source
Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim +4 more
wiley +1 more source
Artificial intelligence in pharmacovigilance: advancing drug safety monitoring and regulatory integration. [PDF]
Nagar A, Gobburu J, Chakravarty A.
europepmc +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium-glucose cotransporter 2 inhibitor users. [PDF]
Le H +5 more
europepmc +1 more source

