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High-Frequency, At-Home Monitoring of Drug Safety and Tolerability in Clinical Trials: Results From Studies of Fluvoxamine for COVID-19 Treatment. [PDF]
Clin Transl SciLenze EJ +10 more
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The Missing Enzymes: A Call to Update Pharmacological Profiling Practices for Better Drug Safety Assessment. [PDF]
J Med ChemMaciag M, Karamyan VT.
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Functional 3D Human Neuron-Glioblastoma Model Reveals Cellular Interactions Enabling Drug Safety Assessments. [PDF]
FASEB JFörster N +7 more
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Drug safety, drug quality, drug analysis
Journal of Pharmaceutical and Biomedical Analysis, 2008Controlling and minimizing the side effects of drugs are the key issues in assuring the safety of drug therapy. Since side effects are inherent properties of the drug material, these cannot be influenced by drug analysts. At the same time drug analysts play a predominant role in assuring the quality of bulk drug materials and drug formulations and this
Sándor Görög
exaly +3 more sources
Current Pharmaceutical Design, 2012
The operating room offers a unique setting where anesthetics, preoperative medications, patient comorbidities, and surgery all merge. Anesthesiologists are responsible for combining these concerns into a dependable and safe approach. From formulation to administration, enhancements in nearly every aspect of a given drug have improved the ability of ...
J Adam, Cartwright +5 more
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The operating room offers a unique setting where anesthetics, preoperative medications, patient comorbidities, and surgery all merge. Anesthesiologists are responsible for combining these concerns into a dependable and safe approach. From formulation to administration, enhancements in nearly every aspect of a given drug have improved the ability of ...
J Adam, Cartwright +5 more
openaire +2 more sources
Expert Opinion on Drug Safety, 2005
The safety of obesity drugs has historically been poor. This and the stigmatisation of obesity in society ensured that a higher standard of safety for obesity drugs must be met. The authors review the safety disasters of obesity drugs that were withdrawn.
Frank L, Greenway, Mary K, Caruso
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The safety of obesity drugs has historically been poor. This and the stigmatisation of obesity in society ensured that a higher standard of safety for obesity drugs must be met. The authors review the safety disasters of obesity drugs that were withdrawn.
Frank L, Greenway, Mary K, Caruso
openaire +2 more sources
JAMA, 1964
NOW, BY LAW, new drugs must be both effective and relatively safe. But I think a new drug must be more than a tolerable cipher in an already overcrowded list. The hope of significant new knowledge which may lead to therapeutic progress is, in my view, the only defense for studying the effects of as yet poorly understood new drugs in human subjects. How
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NOW, BY LAW, new drugs must be both effective and relatively safe. But I think a new drug must be more than a tolerable cipher in an already overcrowded list. The hope of significant new knowledge which may lead to therapeutic progress is, in my view, the only defense for studying the effects of as yet poorly understood new drugs in human subjects. How
openaire +2 more sources
Nursing Standard, 1991
Atenolol or nifedipine can probably be used safely in patients with claudication and coexisting hypertension and angina.
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Atenolol or nifedipine can probably be used safely in patients with claudication and coexisting hypertension and angina.
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2010
The occurrence of sometimes life-threatening adverse drug reactions (ADRs) jeopardizes patients’ health during drug treatment and additionally imposes an increased financial burden on the healthcare system. The withdrawal of already marketed drugs because of ADRs furthermore erodes public confidence in the way drugs are approved.
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The occurrence of sometimes life-threatening adverse drug reactions (ADRs) jeopardizes patients’ health during drug treatment and additionally imposes an increased financial burden on the healthcare system. The withdrawal of already marketed drugs because of ADRs furthermore erodes public confidence in the way drugs are approved.
openaire +1 more source