Results 1 to 10 of about 5,798,552 (267)
Urine screening for drugs [PDF]
British Journal of Psychiatry, 1997 Roy Browne +4 more
openalex +3 more sources
Nature Biotechnology, 2023 The lack of registered drugs for nonalcoholic fatty liver disease (NAFLD) is partly due to the paucity of human-relevant models for target discovery and compound screening.
D. Hendriks +11 more
semanticscholar +1 more source
Advanced Healthcare Materials, 2023 The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since establishing the 2D in vitro cell culture method, the scientific community has improved cell‐based ...
Beatriz D Cardoso +3 more
semanticscholar +1 more source
Recent Advances in Organ‐on‐Chips Integrated with Bioprinting Technologies for Drug Screening
Advanced Healthcare Materials, 2023 Currently, the demand for more reliable drug screening devices has made scientists and researchers develop novel potential approaches to offer an alternative to animal studies.
Nima Tabatabaei Rezaei +5 more
semanticscholar +1 more source
Structural Basis of VSIG3: The Ligand for VISTA
Frontiers in Immunology, 2021 B7 family members and their receptors play key roles in regulating T cell responses, and constitute very attractive targets for developing immunotherapeutic drugs.
Xiaoxue Xie +7 more
doaj +1 more source
Brain organoids are new tool for drug screening of neurological diseases
Neural Regeneration Research, 2023 At the level of in vitro drug screening, the development of a phenotypic analysis system with high-content screening at the core provides a strong platform to support high-throughput drug screening. There are few systematic reports on brain organoids, as
Jin-Qi Zhou +7 more
semanticscholar +1 more source
Identification of active small-molecule modulators targeting the novel immune checkpoint VISTA
BMC Immunology, 2021 Background Cancer immunotherapy has gained increasing popularity as a novel approach to treat cancer. A member of the B7 family, V-domain immunoglobulin suppressor of T-cell activation (VISTA) is a novel immune checkpoint that regulates a broad spectrum ...
Ting-ting Li +7 more
doaj +1 more source
Cell Death Discovery, 2023 Palmitoylation of proteins plays important roles in various physiological processes, such as cell proliferation, inflammation, cell differentiation etc. However, inhibition of protein palmitoylation has led to few new drugs to date.
Yumeng Wang +7 more
doaj +1 more source
Nature Communications, 2021 Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical ...
Jong-Chan Park +14 more
semanticscholar +1 more source
Scientific Reports, 2021 Rhamnan sulphate (RS), a sulphated polysaccharide from Monostroma nitidum, possesses several biological properties that help in treating diseases such as viral infection, thrombosis, and obesity.
Yasuhito Shimada +7 more
doaj +1 more source