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NMR screening in drug discovery
Current Opinion in Biotechnology, 1999NMR methods in drug discovery have traditionally been used to obtain structural information for drug targets or target-ligand complexes. Recently, it has been shown that NMR may be used as an alternative approach for identification of ligands that bind to protein drug targets, shifting the emphasis of many NMR laboratories towards screening and design ...
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Virtual Screening in Drug Design
2013Virtual screening has become a standard tool in drug discovery to identify novel lead compounds that target a biomolecule of interest. I present several concepts in ligand-based and structure-based virtual screening and discuss some of the current shortcomings and new developments.
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Journal of Cardiovascular Pharmacology, 2011
Current drug screening methods are insufficiently predictive of clinical toxicity and efficacy. Recent advances in stem cell technology have the potential to improve drug screening. For tests of cardiotoxicity and efficacy of cardioactive drugs, cardiomyocytes derived from human embryonic stem cells and/or human induced pluripotent stem cells ...
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Current drug screening methods are insufficiently predictive of clinical toxicity and efficacy. Recent advances in stem cell technology have the potential to improve drug screening. For tests of cardiotoxicity and efficacy of cardioactive drugs, cardiomyocytes derived from human embryonic stem cells and/or human induced pluripotent stem cells ...
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Drug Interaction Screening—A Screen or a Sieve?
American Journal of Health-System Pharmacy, 1978W A, Gouveia, R R, Miller
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Social determinants of health and US cancer screening interventions: A systematic review
Ca-A Cancer Journal for Clinicians, 2023Ariella R Korn +2 more
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