Results 251 to 260 of about 1,620,706 (306)
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Anticoccidial drugs: Screening methods
Experimental Parasitology, 1970Abstract A review of thirteen primary screens for anticoccidial activity utilizing Eimeria tenella as the screening organism in chicks reveals differences among the following: breeds of birds used, number and sex of birds used per compound; number of oocysts used for inoculation; time of oocyst administration; experimental diets; and criteria used ...
R F, Shumard, M E, Callender
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American Journal of Health-System Pharmacy, 1977
Screening criteria for adult use of 40 drugs and pediatric use of 10 drugs are presented. The reasons for presenting the criteria are to (1) document the specific screening criteria applied in a number of drug usage review studies, (2) provide a starting point for other groups wishing to develop criteria for drug usage review and (3) seek comments to ...
B M, Brandon +3 more
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Screening criteria for adult use of 40 drugs and pediatric use of 10 drugs are presented. The reasons for presenting the criteria are to (1) document the specific screening criteria applied in a number of drug usage review studies, (2) provide a starting point for other groups wishing to develop criteria for drug usage review and (3) seek comments to ...
B M, Brandon +3 more
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Antiepileptic Drug Development: II. Anticonvulsant Drug Screening
Epilepsia, 1978SummaryBy means of the maximal electroshock seizure (MES) test, the subcutaneous pentylenetetrazol (PTZ) seizure threshold test, and the Rotorod minimal neurotoxicity test, the Anticonvulsant Screening Project has evaluated the activity of 1,495 experimental compounds accessioned in the first 2 years.
R L, Krall +4 more
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Biometrika, 1963
The problem of drug screening is to select from a large number of drugs those having some particular desirable biological effect. A sample of laboratory animals are treated with the drug and some measure of the effect on each animal is obtained. These experimental results lead to the decision to 'accept' or 'reject' the drug.
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The problem of drug screening is to select from a large number of drugs those having some particular desirable biological effect. A sample of laboratory animals are treated with the drug and some measure of the effect on each animal is obtained. These experimental results lead to the decision to 'accept' or 'reject' the drug.
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Neonatal Network, 2016
AbstractGestational substance exposure continues to be a significant problem. Neonates may be exposed to various substances including illicit drugs, prescription drugs, and other legal substances that are best not used during pregnancy because of their potential deleterious effects as possible teratogens or their potential to create dependence and thus
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AbstractGestational substance exposure continues to be a significant problem. Neonates may be exposed to various substances including illicit drugs, prescription drugs, and other legal substances that are best not used during pregnancy because of their potential deleterious effects as possible teratogens or their potential to create dependence and thus
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Nature Biotechnology, 2001
Cell lines that differ by a single genetic change show promise in drug screens to identify compounds with gene-selective properties.
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Cell lines that differ by a single genetic change show promise in drug screens to identify compounds with gene-selective properties.
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JAMA: The Journal of the American Medical Association, 1990
In 1977, Norman Zinberg, MD, invited me to join a panel that he was forming to prepare a report for President Carter's Commission on Mental Health. The title of the panel, the "Liaison Panel on Psychoactive Drug Use/Misuse," underscored the primary theme of the committee's discussions— that a distinction needed to be made between the relatively benign ...
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In 1977, Norman Zinberg, MD, invited me to join a panel that he was forming to prepare a report for President Carter's Commission on Mental Health. The title of the panel, the "Liaison Panel on Psychoactive Drug Use/Misuse," underscored the primary theme of the committee's discussions— that a distinction needed to be made between the relatively benign ...
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Drug screening in “normal” controls
Biological Psychiatry, 1995Recreational drug intoxication or recent use can have profound effects on many dependent measures in biological psychiatry. Despite this, toxicological screening for drugs of abuse in control comparison groups is frequently not done. In 1993, 70 studies published in the American Journal of Psychiatry included nonpsychiatric-disordered comparison groups,
N R, Swerdlow +4 more
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Computational Screening of Drug Solvates
Pharmaceutical Research, 2016Solvates are mainly undesired by-products during the pharmaceutical development of new drugs. In addition, solvate formation may also distort solubility measurements. The presented study introduces a simple computational approach that allows for the identification of drug solvent pairs which most likely form crystalline solid phases.The mixing enthalpy
Christoph Loschen, Andreas Klamt
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JAMA: The Journal of the American Medical Association, 1992
To the Editor. —After reading the article "The Efficacy of Preemployment Drug Screening for Marijuana and Cocaine in Predicting Employment Outcome,"1 I decided to summarize an unpublished study that I recently completed.
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To the Editor. —After reading the article "The Efficacy of Preemployment Drug Screening for Marijuana and Cocaine in Predicting Employment Outcome,"1 I decided to summarize an unpublished study that I recently completed.
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