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Drug Sensitization, Substance Abuse, and Chemical Sensitivity
Toxicology and Industrial Health, 1994Substance abuse, involving drugs such as cocaine, heroin, alcohol, marijuana, nicotine, barbiturates, etc., is by far by the most prevalent psychiatric disorder. Much has been learned about the abuse of these substances that may be useful to consider in designing and analyzing research concerning multiple chemical sensitivities (MCS).
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Sensitization Processes in Drug Addiction
2009In 1993, Robinson and Berridge published their first review that laid out the incentive sensitization theory of addiction (Robinson and Berridge 1993 Brain Res Rev 18:247). Its basic point is that repeated exposure to drugs of abuse causes hypersensitivity to drugs and drug-associated stimuli of the neural circuits mediating incentive salience, an ...
Louk J M J, Vanderschuren +1 more
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Tolerance and sensitization to the behavioral effects of drugs
Behavioural Pharmacology, 1993Tolerance and sensitization are relatively simple manifestations of learning and memory that refer to decreases and increases in the strength of a response to a stimulus induced by past experiences with the same or related stimuli. In the context of the study of drugs, tolerance refers to the decreased effectiveness of a given drug with repeated ...
STEWART J, BADIANI, Aldo
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Allergy and Drug Sensitivity of Skin
Annual Review of Pharmacology, 1969Human skin is the most evolved organ of man and is thought to be primarily responsible for his wide habitat. It is also different from animal skin in that large areas are relatively devoid of hair and have abundant eccrine sweat glands and a vast network of thermosensitive responsive blood vessels.
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Behavior Genetics of Drug Sensitization
Critical Reviews™ in Neurobiology, 1997Recent history has seen a surge of interest in the phenomenon of drug sensitization (reverse tolerance), in part because sensitization has been suggested as an important factor in the development of drug abuse. Genetic variation plays a key role in sensitivity to many drug effects, as well as predilection toward alcohol and drug abuse. The goal of this
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Shanu Modi +2 more
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Drug Tolerance and Sensitization
1989Any reader of this book who is familiar with the reviews on alcohol and drug tolerance published during the 1970s cannot help but be struck by the marked elaboration of knowledge and concepts concerning tolerance that have taken place in the past 10–15 ys. This is particularly true of the behavioral aspects of the subject.
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Drug sensitivity in the elderly
1979The observation that the response of elderly patients to drugs differs from the response seen in younger patients is not new nor is it surprising. The effect of increasing age on drug activity was the subject of a series of early studies conducted in the 1940s by K. K. Chen and his colleagues at Eli Lilly.
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