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Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
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Signaling and drug sensitivity
Cancer and Metastasis Reviews, 1994Even though alterations in receptor and nonreceptor kinases are involved in the development of human cancer, many cancer cell lines still retain their responsiveness to growth factors. We have investigated the hypothesis that cellular signaling events regulate the sensitivity of cancer cells to chemotherapeutic agents.
R D, Christen +9 more
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High-Sensitivity Antitumor Drug Sensitivity Testing
Oncology, 2009For antitumor drug sensitivity testing we have been performing the succinic dehydrogenase inhibition test using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphe-nyltetrazolium bromide (MTT). A new tetrazolium salt 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenyl-amino) carbonyl]-2H-tetrazolium hydroxide (XTT) has been synthesized recently, and we have been ...
T, Kondo +4 more
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Journal Of Clinical Psychopharmacology, 1990
Thirty noninsomniac healthy adult men were enrolled in a multicenter pilot study to evaluate the sensitivity of psychomotor and cognitive tasks and subjective evaluation of performance and mood after treatment with flurazepam (Dalmane) 45 mg (larger than the recommended prescribing dose of 15-30 mg).
H, Moskowitz, D, Chen
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Thirty noninsomniac healthy adult men were enrolled in a multicenter pilot study to evaluate the sensitivity of psychomotor and cognitive tasks and subjective evaluation of performance and mood after treatment with flurazepam (Dalmane) 45 mg (larger than the recommended prescribing dose of 15-30 mg).
H, Moskowitz, D, Chen
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Electrode Sensitive to Sulfa Drugs
Journal of Pharmaceutical Sciences, 1976An electrode sensitive to sulfa drugs was constructed by using the iron(II)-bathophenanthroline chelate embedded in a liquid membrane. Rapid and Nernstian responses were exhibited against solutions of sulfamerazine and sulfisomidine ranging between 10(-3) and 10(-1) M in concentration.
N, Hazemoto, N, Kamo, Y, Kobatake
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Cell Cycle and Drug Sensitivity
2005Induction of tumor cell death by chemotherapeutic modalities often occurs in a cell cycle-dependent manner. It has also been observed that several regulatory proteins involved in tumor chemosensitivity and apoptosis are expressed periodically during the cell cycle progression.
Aslamuzzaman, Kazi, Q Ping, Dou
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Tolerance and sensitization to the behavioral effects of drugs
Behavioural Pharmacology, 1993Tolerance and sensitization are relatively simple manifestations of learning and memory that refer to decreases and increases in the strength of a response to a stimulus induced by past experiences with the same or related stimuli. In the context of the study of drugs, tolerance refers to the decreased effectiveness of a given drug with repeated ...
STEWART J, BADIANI, Aldo
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