Results 1 to 10 of about 6,529,623 (190)
Drug Stability Analysis by Raman Spectroscopy [PDF]
Pharmaceutics, 2014 Pharmaceutical drugs are available to astronauts to help them overcome the deleterious effects of weightlessness, sickness and injuries. Unfortunately, recent studies have shown that some of the drugs currently used may degrade more rapidly in space ...
Chetan Shende +3 more
doaj +5 more sources
Cyclodextrins and Their Derivatives as Drug Stability Modifiers
Pharmaceuticals, 2023 Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion complexes with many substances.
V. Aiassa +3 more
semanticscholar +5 more sources
Drug Stability: ICH versus Accelerated Predictive Stability Studies
Pharmaceutics, 2022 The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), along with the World Health Organization (WHO), has provided a set of guidelines (ICH Q1A-E, Q3A-B, Q5C, Q6A-B) intended to unify the standards
Olga González-González +6 more
doaj +2 more sources
Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability [PDF]
Pharmaceutics, 2018 Many approaches have been developed over time to overcome the bioavailability limitations of poorly soluble drugs. With the advances in nanotechnology in recent decades, science and industry have been approaching this issue through the formulation of ...
M. Gigliobianco +3 more
semanticscholar +8 more sources
Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters [PDF]
Molecular Pharmaceutics, 2015 The purpose of this study was to develop a predictive model of the amorphous stability of drugs with particular relevance for poorly water-soluble compounds.
Katarzyna Nurzyńska +5 more
openalex +2 more sources
Compressed Oxygen in Drug Stability Experiments
Chemical and Pharmaceutical Bulletin, 2007 A drug stability experiment accelerated by compressed oxygen was established. The stability of 10% ascorbic acid solution as a model was studied and the kinetic parameters were obtained with the newly established experimental method. Because ascorbic acid degrades under both anaerobic and aerobic conditions, the total rate constant k(total) can be ...
Yan Shi +6 more
openalex +5 more sources
Stability of furosemide and torasemide in parenteral nutrition admixture [PDF]
Acta Poloniae Pharmaceutica, 2023 Furosemide and torasemide (loop diuretics) are used to treat hypertension or pulmonary edema. They are often administered in the parenteral route. In critically ill patients, there is a problem of a limited number of venous accesses, which complicates ...
Szymon Tomczak +2 more
doaj +1 more source
Stability Tests and Analytical Methods of Tacrolimus: A Review [PDF]
ImmunoAnalysis, 2022 Tacrolimus is an immunosuppressive drug widely used in organ or tissue transplantation. Furthermore, its anti-inflammatory effects are employed in treatments for psoriasis, uveitis, and vernal keratoconjunctivitis.
Sara Sajjadi +2 more
doaj +1 more source
The Journal of pharmacy and pharmacology, 2023 Pharmaceutical co-crystals have gained significant attention in recent years as a promising green and sustainable method for poorly soluble drugs to improve their solubility, stability, and bioavailability.
Anisha Chettri +3 more
semanticscholar +1 more source