Results 21 to 30 of about 8,056,631 (393)

Challenges of Dissolution Methods Development for Soft Gelatin Capsules

open access: yesPharmaceutics, 2021
Recently, the development of soft gelatin capsules (SGCs) dosage forms has attracted a great deal of interest in the oral delivery of poorly water-soluble drugs.
Festo Damian   +4 more
doaj   +1 more source

Review of binary, ternary and quaternary mixtures for induction and maintenance of opioid free anesthesia [PDF]

open access: yesFarmacia Hospitalaria, 2021
Objective: To describe and organize the current information available on binary, ternary and/or quaternary mixtures used in opioid-free anesthesia (OFA), as well as their physicochemical stability, in order to facilitate its correct administration ...
Beatriz Tauste-Hernández   +3 more
doaj   +1 more source

Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug-Polymer Interactions.

open access: yesMolecular Pharmaceutics, 2021
Amorphous solid dispersions (ASDs) are of great interest due to their ability to enhance the delivery of poorly soluble drugs. Recent studies have shown that, in addition to acting as a crystallization inhibitor, the polymer in an ASD plays a role in ...
Tze Ning Hiew, D. Zemlyanov, L. Taylor
semanticscholar   +1 more source

Chemical Stability of Metal‐organic Frameworks for Applications in Drug Delivery

open access: yesChemNanoMat, 2021
Structural variety, tunable porosity and opportunities for functionalization make metal-organic frameworks (MOFs) promising materials for applications in medicine as drug delivery systems.
Hana Bunzen
semanticscholar   +1 more source

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]

open access: yes, 2015
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra   +5 more
core   +1 more source

Ileocolonic-Targeted JAK Inhibitor: A Safer and More Effective Treatment for Inflammatory Bowel Disease

open access: yesPharmaceutics, 2022
Janus kinase (JAK) inhibitors, such as tofacitinib (Xeljanz) and filgotinib (Jyseleca), have been approved for treatment of ulcerative colitis with several other JAK inhibitors in late-stage clinical trials for inflammatory bowel disease (IBD).
Vipul Yadav   +16 more
doaj   +1 more source

Hydrogen-bonded multilayer thin films and capsules based on poly(2-n-propyl-2-oxazoline) and tannic acid : investigation on intermolecular forces, stability, and permeability [PDF]

open access: yes, 2019
In recent years, hydrogen-bonded multilayer thin films and capsules based on neutral and nontoxic building blocks have been receiving interest for the design of stimuli-responsive drug delivery systems and for the preparation of thin-film coatings ...
Hoogenboom, Richard   +5 more
core   +1 more source

A systematic approach to the formulation of anti-onychomycotic nail patches [PDF]

open access: yes, 2018
Nail patches have a potential role as drug carriers for the topical treatment of nail diseases such as onychomycosis, a common condition. O ur aim was therefore to develop a systematic and novel appr oach to the formulat ion of a simple drug -in-adhesive
Charalambides, MN   +5 more
core   +1 more source

Potencial hidrogeniônico de soluções de cloridrato de dobutamina expostas a condições ambientais de unidades de cuidados intensivos neonatais Hydrogen-ion potential of dobutamine hydrochloride solutions exposed to environmental conditions of neonatal intensive care units

open access: yesJornal de Pediatria, 2009
OBJETIVO: Verificar o potencial hidrogeniônico (pH) de soluções de cloridrato de dobutamina sob condições ambientais que mimetizam unidades de cuidados intensivos neonatais.
Lidiane L. Reis   +2 more
doaj   +1 more source

Prevalence of tablet splitting in a Brazilian tertiary care hospital

open access: yesPharmacy Practice, 2020
Background: Although a highly common practice in hospital care, tablet splitting can cause dose variation and reduce drug stability, both of which impair drug therapy. Objective: To determine the overall prevalence of tablet splitting in hospital care
Vivianne V. Melo   +6 more
doaj   +1 more source

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