Results 41 to 50 of about 3,800,890 (227)

Development of gradient diffusion strips to identify the potentiating effect of antimicrobial compounds against multidrug-resistant Klebsiella pneumoniae strains [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. The aim of the study was to develop gradient diffusion strips with substances capable of potentiating the action of antibiotics for the treatment of infections caused by multidrug-resistant strains of K. pneumoniae.
Likhachev I.V., Kaftyreva L.A., Samoilova A.A., Kraeva L.A., Mikhailov N.V.   +4 more
doaj   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Associated with Mycoplasma pneumoniae Infection

Case Reports in Dermatology, 2020
Mycoplasma infection may lower the threshold for drug allergy in particular patients. We present a case of drug reaction with eosinophilia and systemic symptoms (DRESS), with drug etiology and non-drug etiology (Mycoplasma infection).
Guy Shalom, Raed Khoury, Amir Horev
doaj   +1 more source

Hemodynamic Effects of Co-administration of Midazolam during Anesthesia Induction with Propofol and Remifentanil in Hypertensive Patients [PDF]

Kosin Medical Journal, 2017
Objectives Propofol, midazolam and remifentanil are commonly used for clinical anesthesia. We compared the effects of midazolam-propofol-remifentanil and propofol-remifentanil on hemodynamic responses during anesthesia induction in hypertensive patients.
Ju Deok Kim, Joo Won Kim, His Chiang Kung, Jun Hong Kang, Hye Young Shin, Doo Sik Kim, Sie Jeong Ryu, Kyung Han Kim   +7 more
doaj   +1 more source

AnRPackage for Assessing Drug Synergism/Antagonism [PDF]

Journal of Statistical Software, 2010
Synergistic and antagonistic drug interactions are important to consider when developing mixtures of anticancer or other types of drugs. Boik, Newman, and Boik (2008) proposed the MixLow method as an alternative to the Median-Effect method of Chou and Talalay (1984) for estimating drug interaction indices. One advantage of the MixLow method is that the
Balasubramanian Narasimhan, John C. Boik
openaire   +4 more sources

Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1

Cells, 2020
Cancer stem cells (CSCs) represent rare tumor cell populations capable of self-renewal, differentiation, and tumor initiation and are highly resistant to chemotherapy and radiotherapy.
Ling-Wei Hii, Felicia Fei-Lei Chung, Chun Wai Mai, Zong Yang Yee, Hong Hao Chan, Vijay Joseph Raja, Noah Elias Dephoure, Nigel J. Pyne, Susan Pyne, Chee-Onn Leong   +9 more
doaj   +1 more source

Synergistic anti-allodynic effect between intraperitoneal thalidomide and morphine on rat spinal nerve ligation-induced neuropathic pain [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundThalidomide has been recognized as having an anti-allodynic effect against neuropathic pain induced by spinal nerve ligation. Its clinical beneficial effects are mainly derived from its immune-modulating property, which is known to influence ...
Hyung Gon Lee, Woong Mo Kim, Myung Ha Yoon, A Reum Park, Jeong-Il Choi   +4 more
doaj   +1 more source

Supramolecular assemblies of rifampicin and cationic bilayers: preparation, characterization and micobactericidal activity

BMC Biotechnology, 2011
Background Cationic bilayers based on the inexpensive synthetic lipid dioctadecyldimethylammonium bromide (DODAB) have been useful as carriers for drug delivery, immunoadjuvants for vaccines and active antimicrobial agents.
Mamizuka Elsa M, Barbassa Lilian, Carmona-Ribeiro Ana M   +2 more
doaj   +1 more source

In vitro effectivity of three approved drugs and their synergistic interaction against Leishmania infantum

Biomédica: revista del Instituto Nacional de Salud, 2020
Introduction: Leishmaniasis remains one of the neglected tropical diseases. Repurposing existing drugs has proven to be successful for treating neglected tropical diseases while combination therapy is a strategic alternative for the treatment of ...
Iman Fathy Abou-El-Naga, Rasha Fadly Mady, Nermine Mogahed Fawzy Hussien Mogahed   +2 more
doaj   +1 more source

Increasing the Efficacy of Treatment of Staphylococcus aureus–Candida albicans Mixed Infections with Myrtenol

Antibiotics, 2022
Infectious diseases caused by various nosocomial microorganisms affect worldwide both immunocompromised and relatively healthy persons. Bacteria and fungi have different tools to evade antimicrobials, such as hydrolysis damaging the drug, efflux systems,
Ruba Y. Mahmoud, Elena Y. Trizna, Rand K. Sulaiman, Roman S. Pavelyev, Ilmir R. Gilfanov, Svetlana A. Lisovskaya, Olga V. Ostolopovskaya, Larisa L. Frolova, Alexander V. Kutchin, Galina B. Guseva, Elena V. Antina, Mikhail B. Berezin, Liliya E. Nikitina, Airat R. Kayumov   +13 more
doaj   +1 more source

Fungicidal action of geraniol against Candida albicans is potentiated by abrogated CaCdr1p drug efflux and fluconazole synergism

PLoS ONE, 2018
Among the several mechanisms of multidrug resistance (MDR), overexpression of drug efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major facilitator superfamily (MFS) respectively remain the predominant mechanisms of candidal
Shweta Singh, Z. Fatima, K. Ahmad, S. Hameed   +3 more
semanticscholar   +1 more source