Arthritis Care &Research, Accepted Article.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Advanced Biology, EarlyView.Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source
Capitalist Reproduction in Schooling: The social control of marginalized students through zero tolerance policies [PDF]
, 2019 Due to increasing media focus, there has been growing concern that U.S. students and the school environment are increasingly violent, leading the public to believe that school discipline should become more strict and punitive (Giroux 2003; Schept, Wall, &
Wickline, Mary K
core +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
, 2014 Practically, all chemotherapeutic agents lead to drug resistance. Clinically, it is a challenge to determine whether resistance arises prior to, or as a result of, cancer therapy.
A. Lorz +37 more
core +1 more source
Compounding Effects of Climate Warming and Antibiotic Resistance. [PDF]
, 2020 Bacteria have evolved diverse mechanisms to survive environments with antibiotics. Temperature is both a key factor that affects the survival of bacteria in the presence of antibiotics and an environmental trait that is drastically increasing due to ...
Cruz-Loya, Mauricio +4 more
core +1 more source
Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials
Advanced Engineering Materials, EarlyView.This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani +4 more
wiley +1 more source
Long-Lasting Changes in Morphine-Induced Locomotor Sensitization and Tolerance in Long-Evans Mother Rats as a Result of Periodic Postpartum Separation from the Litter: A Novel Model of Increased Vulnerability to Drug Abuse? [PDF]
, 2002 Mikhail Kalinichev +2 more
openalex +1 more source
3D Printed Ultra‐Fast Plastic Scintillators Based on Perovskite‐Photocurable Polymer Composite
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.The demand for radiation detection is increasing in a number of fields, including high‐energy physics, medical imaging, and homeland security. This study serves to demonstrate the potential for the fabrication of fast perovskite‐based scintillators with complex shapes via stereolithographic additive manufacturing, representing a new path toward the ...
Antonella Giuri +16 more
wiley +1 more source
Preclinical Assessment of Gastrooesophageal Tolerance of the New Antiosteoporotic Drug Strontium Ranelate: An Endoscopic Study in Monkeys [PDF]
, 2006 C Fisch +5 more
openalex +1 more source