Why Do Some People Want to Legalize Cannabis Use? [PDF]
Preferences and attitudes to illicit drug policy held by individuals are likely to be an important in uence in the development of illicit drug policy.
Grossmann, M. +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Polypharmacy Among Prescription Drug Users [PDF]
, 2017 Polypharmacy, i.e., the misuse of multiple prescription drugs or prescription medication with other substances, is highly problematic. Whether unintentional or deliberate, misuse of multiple drugs can lead to adverse effects including addiction; drug ...
Greene, Marion S., Omenka, Issac
core +1 more source
The Five Factor Model of personality and evaluation of drug consumption risk
, 2017 The problem of evaluating an individual's risk of drug consumption and misuse is highly important. An online survey methodology was employed to collect data including Big Five personality traits (NEO-FFI-R), impulsivity (BIS-11), sensation seeking (ImpSS)
A. Terracciano +38 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Comparison of the Effectiveness of Cognitive Bias Correction in Real and Placebo Modes
Armaghane Danesh Bimonthly Journal, 2019 Background & aim: Inability to control drug use is one of the main aspects of drug dependence. Part of this disability is due to the cognitive biases that result from people's constant exposure to substances.
F Zeraat Herfeh +2 more
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Transitions from Compulsory Detention to Community-Based Treatment: No Transparency without Data, No Accountability without Independent Evaluations [PDF]
Health and Human Rights, 2022 Pascal Tanguay +2 more
doaj
Concept of harm reduction: part 1
Journal of Health Science and Medical Research (JHSMR), 2007 A Thai government policy taking measures to curb the use of illicit drugs has changed the pattern of use away from heroin to other alternatives such as dormicum (Midazolam), hypnotics, and alcohol, which are not suitable for intravenous injection ...
N Apakupakul
doaj
Directly Observed Therapy with Azithromycin for Skin and Soft Tissue Infections in Injection Drug Users [PDF]
, 2007 Harout Tossonian +7 more
openalex +1 more source